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EC 1.2.3.7 Details
show Brenda entryEC number
1.2.3.7
Accepted name
indole-3-acetaldehyde oxidase
Reaction
(indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2
Other name(s)
indoleacetaldehyde oxidase,
IAAld oxidase,
AO1,
indole-3-acetaldehyde:oxygen oxidoreductase
Systematic name
(indol-3-yl)acetaldehyde:oxygen oxidoreductase
CAS registry number
66082-22-2
Comment
A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC 1.2.3.1). It has a preference for aldehydes having an indole-ring structure as substrate [6,7]. It may play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1, than in wild-type Arabidopsis thaliana [7]. While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly. The enzyme from maize contains FAD, iron and molybdenum [4].
History
created 1984, modified 2004, modified 2006
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.2.3.2 created 1961, deleted 1984 1.2.3.10 created 1990, deleted 2003 1.2.3.12 created 2000, deleted 2003 1.6.2.1 created 1961, deleted 1965 1.6.2.3 created 1972, deleted 1965
