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Information on EC 1.2.3.7 - indole-3-acetaldehyde oxidase

for references in articles please use BRENDA:EC1.2.3.7
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IUBMB Comments
A hemoprotein. This enzyme is an isoform of aldehyde oxidase (EC 1.2.3.1). It has a preference for aldehydes having an indole-ring structure as substrate [6,7]. It may play a role in plant hormone biosynthesis as its activity is higher in the auxin-overproducing mutant, super-root1, than in wild-type Arabidopsis thaliana . While (indol-3-yl)acetaldehyde is the preferred substrate, it also oxidizes indole-3-carbaldehyde and acetaldehyde, but more slowly. The enzyme from maize contains FAD, iron and molybdenum .
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
AAO1, AOgamma, IAAld oxidase, indoleacetaldehyde oxidase, oxidase, indoleacetaldehyde, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(indol-3-yl)acetaldehyde + H2O + O2 = (indol-3-yl)acetate + H2O2
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