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EC 3.4.11.15 Details
EC number
3.4.11.15
Accepted name
aminopeptidase Y
Reaction
Preferentially, release of N-terminal lysine
Other name(s)
aminopeptidase Co,
aminopeptidase (cobalt-activated),
lysyl aminopeptidase
CAS registry number
114796-97-3
Comment
Requires Co2+; inhibited by Zn2+ and Mn2+. An enzyme best known from Saccharomyces cerevisiae that hydrolyses Lys-NHPhNO2 and, more slowly, Arg-NHPhNO2. Type example of peptidase family M28
History
created 1989, modified 1997
EC Tree
3.4.11.8 created 1972, deleted 1981
3.4.11.11 created 1978, deleted 1992
3.4.11.12 created 1978, deleted 1997