EC Explorer
[browse EC tree] - [search]
EC 1.14.20.14 Details
EC number
1.14.20.14
Accepted name
hapalindole-type alkaloid chlorinase
Reaction
(1) hapalindole U + 2-oxoglutarate + O2 + chloride = hapalindole G + succinate + CO2 + H2O;; (2)12-epi-fischerindole U + 2-oxoglutarate + O2 + chloride = 12-epi-fischerindole G + succinate + CO2 + H2O
Other name(s)
ambO5 (gene name),
welO5 (gene name)
Systematic name
12-epi-fischerindole U,2-oxoglutarate:oxygen oxidoreductase (13-halogenating)
Comment
The enzyme, characterized from hapalindole-type alkaloids-producing cyanobacteria, is a specialized iron(II)/2-oxoglutarate-dependent oxygenase that catalyses the chlorination of its substrates in a reaction that requires oxygen, chloride ions, iron(II) and 2-oxoglutarate.
History
created 2018
EC Tree