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EC 1.8.4.8 Details
show Brenda entryEC number
1.8.4.8
Accepted name
phosphoadenylyl-sulfate reductase (thioredoxin)
Reaction
adenosine 3′,5′-bisphosphate + sulfite + thioredoxin disulfide = 3′-phosphoadenylyl sulfate + thioredoxin
Other name(s)
PAPS reductase, thioredoxin-dependent,
PAPS reductase,
thioredoxin:adenosine 3′-phosphate 5′-phosphosulfate reductase,
3′-phosphoadenylylsulfate reductase,
thioredoxin:3′-phospho-adenylylsulfate reductase,
phosphoadenosine-phosphosulfate reductase,
adenosine 3′,5′-bisphosphate,sulfite:oxidized-thioredoxin oxidoreductase (3′-phosphoadenosine-5′-phosphosulfate-forming)
Systematic name
adenosine 3′,5′-bisphosphate,sulfite:thioredoxin-disulfide oxidoreductase (3′-phosphoadenosine-5′-phosphosulfate-forming)
CAS registry number
9068-63-7
Comment
Specific for PAPS. The enzyme from Escherichia coli will use thioredoxins from other species.
History
created 1999 as EC 1.8.99.4, transferred 2000 to EC 1.8.4.8
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1 Oxidoreductases
1.1.1.70 created 1965, deleted 1978 1.1.1.74 created 1972, deleted 1976 1.1.1.89 created 1972, deleted 1976 1.1.1.109 created 1972, deleted 1976 1.1.1.139 created 1972, deleted 1978 1.1.1.155 created 1976, deleted 2004 1.1.1.171 created 1978, deleted 1984 1.1.1.180 created 1983, deleted 1984 1.1.1.182 created 1983, deleted 1990 1.1.1.204 created 1972 as EC 1.2.1.37, transferred 1984 to EC 1.1.1.204, modified 1989, deleted 2004 1.1.1.242 created 1992, deleted 2001 1.1.1.253 created 1999, deleted 2003
1.1.2 With a cytochrome as acceptor
