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Information on EC 1.8.4.8 - phosphoadenylyl-sulfate reductase (thioredoxin)

for references in articles please use BRENDA:EC1.8.4.8

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IUBMB Comments

Specific for PAPS. The enzyme from Escherichia coli will use thioredoxins from other species.

The enzyme appears in viruses and cellular organisms

Synonyms
aps reductase, paps reductase, adenosine 5'-phosphosulfate reductase, adenosine 3'-phosphate 5'-phosphosulfate reductase, 5'-adenylylsulfate reductase, paps sulfotransferase, 3'-phosphoadenosine 5'-phosphosulfate reductase, 3'-phosphoadenylylsulfate reductase, adenylyl phosphosulfate reductase, cysh1, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
assimilatory sulfate reduction I, assimilatory sulfate reduction IV
Highest Expressing Human Cell Lines
Cell Line Links Gene Links