EC Explorer
[browse EC tree] - [search]
EC 3.1.4.37 Details
show Brenda entryEC number
3.1.4.37
Accepted name
2′,3′-cyclic-nucleotide 3′-phosphodiesterase
Reaction
nucleoside 2′,3′-cyclic phosphate + H2O = nucleoside 2′-phosphate
Other name(s)
cyclic-CMP phosphodiesterase,
2′,3′-cyclic AMP phosphodiesterase,
cyclic 2′,3′-nucleotide 3′-phosphodiesterase,
cyclic 2′,3′-nucleotide phosphodiesterase,
2′,3′-cyclic nucleoside monophosphate phosphodiesterase,
2′,3′-cyclic nucleotide 3′-phosphohydrolase,
CNPase,
2′,3′-cyclic nucleotide phosphohydrolase,
2′:3′-cyclic nucleotide 3′-phosphodiesterase,
2′:3′-CNMP-3′-ase
Systematic name
nucleoside-2′,3′-cyclic-phosphate 2′-nucleotidohydrolase
CAS registry number
60098-35-3
Comment
The brain enzyme acts on 2′,3′-cyclic AMP more rapidly than on the UMP or CMP derivatives. An enzyme from liver acts on 2′,3′-cyclic CMP more rapidly than on the purine derivatives; it also hydrolyses the corresponding 3′,5′-cyclic phosphates, but more slowly. This latter enzyme has been called cyclic-CMP phosphodiesterase.
History
created 1976
back to topEC Tree
1 Oxidoreductases
3 Hydrolases
3.1.4.5 created 1961, deleted 1978 3.1.4.6 created 1961, deleted 1978 3.1.4.7 created 1961, deleted 1978 3.1.4.9 created 1965, deleted 1978 3.1.4.10 created 1972, modified 1976, deleted 2002 3.1.4.18 created 1972, deleted 1978 3.1.4.19 created 1972, deleted 1978 3.1.4.20 created 1972, deleted 1978 3.1.4.21 created 1972, deleted 1978 3.1.4.22 created 1972, deleted 1978 3.1.4.23 created 1972, deleted 1978 3.1.4.24 created 1972, deleted 1978 3.1.4.25 created 1972, deleted 1978 3.1.4.26 created 1972, deleted 1978 3.1.4.27 created 1972, deleted 1978 3.1.4.28 created 1972, deleted 1978 3.1.4.29 created 1972, deleted 1978 3.1.4.30 created 1972, deleted 1978 3.1.4.31 created 1972, deleted 1978 3.1.4.32 created 1972, deleted 1978 3.1.4.33 created 1972, deleted 1978 3.1.4.34 created 1972, deleted 1978 3.1.4.36 created 1976, deleted 2002 3.1.4.47 created 1989, deleted 2002
