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EC 1.13.11.53 Details
show Brenda entryEC number
1.13.11.53
Accepted name
acireductone dioxygenase (Ni2+-requiring)
Reaction
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + O2 = 3-(methylsulfanyl)propanoate + formate + CO
Other name(s)
ARD,
2-hydroxy-3-keto-5-thiomethylpent-1-ene dioxygenase (ambiguous),
acireductone dioxygenase (ambiguous),
E-2,
1,2-dihydroxy-5-(methylthio)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)
Systematic name
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one:oxygen oxidoreductase (formate- and CO-forming)
Comment
Requires Ni2+. If iron(II) is bound instead of Ni2+, the reaction catalysed by EC 1.13.11.54, acireductone dioxygenase [iron(II)-requiring], occurs instead [1]. The enzyme from the bacterium Klebsiella oxytoca (formerly Klebsiella pneumoniae) ATCC strain 8724 is involved in the methionine salvage pathway.
History
created 2006
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1 Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.13.11.21 created 1972, deleted 2001
