EC Explorer

7.4.2.8

protein-secreting ATPase

ATP + H₂O + cellular protein_{[side 1]} = ADP + phosphate + cellular protein_{[side 2]}

ATP phosphohydrolase (protein-secreting)

A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase that is involved in protein transport. There are several families of enzymes included here, e.g. ATP-hydrolysing enzymes of the general secretory pathway (Sec or Type II), of the virulence-related secretory pathway (Type III) and of the conjugal DNA-protein transfer pathway (Type IV). Type II enzymes occur in bacteria, archaea and eucarya, whereas type III and type IV enzymes occur in bacteria where they form components of a multi-subunit complex.

created 2000 as EC 3.6.3.50, transferred 2018 to EC 7.4.2.8