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EC Explorer

EC 1.14.14.125 Details
EC number
1.14.14.125
Accepted name
monacolin L hydroxylase
Reaction
monacolin L acid + O2 + [reduced NADPH—hemoprotein reductase] = monacolin J acid + [oxidized NADPH—hemoprotein reductase] + H2O
Other name(s)
LovA (ambiguous)
Systematic name
monacolin L acid,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating)
Comment
A cytochrome P-450 (heme-thiolate) protein. The enzyme from fungi also catalyses the reaction of EC 1.14.14.124, dihydromonacolin L hydroxylase.
History
created 2014 as EC 1.14.13.198, transferred 2018 to EC 1.14.14.125
EC Tree
1.14.14.2 created 1972, deleted 1976
1.14.14.4 created 2000, deleted 2002