3.4.24.52: trimerelysin I

This is an abbreviated version!
For detailed information about trimerelysin I, go to the full flat file.

Reaction

Cleavage of only two bonds His10-/-Leu and Ala14-/-Leu in the insulin B chain =

Synonyms

Hemorrhagic metalloproteinase HR1A, Hemorrhagic proteinase HR1A, HR1A, Metalloproteinase HR1A, metalloproteinase HR1b, Trimeresurus metalloendopeptidase I

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.24 Metalloendopeptidases

3.4.24.52 trimerelysin I

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Results	in table
7	AA Sequence
1	Application
1	CAS Registry Number
3	Inhibitors
5	KM Value [mM]
1	Localization
3	Metals/Ions
6	Molecular Weight [Da]
4	Natural Substrates/ Products (Substrates)
7	Organism
3	pH Optimum
1	pH Range
1	Posttranslational Modification
2	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
7	Source Tissue
1	Specific Activity [micromol/min/mg]
22	Substrates and Products (Substrate)
3	Subunits
8	Synonyms
3	Temperature Optimum [°C]

KM Value

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KM Value on EC 3.4.24.52 - trimerelysin I

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0.12

2-Aminobenzoyl-Ala-Gly-Leu-Ala-2,4-dinitroanilinoethylamide

Protobothrops flavoviridis

31296

0.014

2-aminobenzoyl-Asn-Ala-Phe-Leu-Ala-2,4-dinitroanilinoethylamide

Protobothrops flavoviridis

31296

0.013

2-Aminobenzoyl-Phe-Ser-Pro-Met-Leu-2,4-dinitroanilinoethylamide

Protobothrops flavoviridis

2-aminobenzoyl-Gly-Phe-Arg-Leu-Leu-2,4-dinitroanilinoethylamide

31296

0.015

2-Aminobenzoyl-Ser-Pro-Met-Leu-2,4-dinitroanilinoethylamide

Protobothrops flavoviridis

31296

0.0076

2-Aminobenzoyl-Thr-Glu-Lys-Leu-Val-2,4-dinitroanilinoethylamide

Protobothrops flavoviridis

31296