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3.4.22.14: actinidain

This is an abbreviated version!
For detailed information about actinidain, go to the full flat file.

Word Map on EC 3.4.22.14

Reaction

Similar to that of papain =

Synonyms

Act d 1, ACT1A-1, ACT1A-2, Actd1, actinidain, actinidia anionic protease, actinidin, mercaptoproteinase A2, proteinase A2 of Actinidia chinensis

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.14 actinidain

Engineering

Engineering on EC 3.4.22.14 - actinidain

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
P75Q
-
the mutant shows reduced activity compared tot he wild type enzyme
proteolytic modification
-
the enzyme is secreted in an inactive form as zymogen, named actininidin, which has a MW of 39000 Da
S68G
-
inactive
S68G/P75Q
-
the mutant shows reduced activity compared tot he wild type enzyme
P75Q
-
the mutant shows reduced activity compared tot he wild type enzyme
S68G
-
inactive
S68G/P75Q
-
the mutant shows reduced activity compared tot he wild type enzyme