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2.5.1.21: squalene synthase

This is an abbreviated version!
For detailed information about squalene synthase, go to the full flat file.

Word Map on EC 2.5.1.21

Reaction

2 (2E,6E)-farnesyl diphosphate +

NAD(P)H
+
H+
=
squalene
+ 2 diphosphate +
NAD(P)+

Synonyms

BbSS, BSS, CrSQS, dt-ySQase, Erg9, EtSS, farnesyl-diphosphate farnesyltransferase, farnesyl-diphosphate:farnesyldiphosphate farnesyltransferase, farnesyldiphosphate farnesyltransferase 1, farnesyldiphosphate:farnesyldiphosphate farnesyltransferase, farnesyltransferase, FDFT1, hSQS, presqualene synthase, presqualene-diphosphate synthase, SgSQS, SQase, SQS, SQS1, SQS2, squalene synthase, squalene synthase 1, squalene synthase 2, squalene synthetase, SS1, SSase, SSN, synthase, squalene, TkSQS1, TkSQS2

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.21 squalene synthase

Expression

Expression on EC 2.5.1.21 - squalene synthase

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EXPRESSION
ORGANISM
UNIPROT
LITERATURE
BfSS1 mRNA accumulates ubiquitously in plant organs and markedly increases in roots after treatment with methyl jasmonate, abscisic acid, and ethephon
expression analysis reveals the coregulation of squalene synthase TkSQS1 and squalene epoxidase TkSQE1, along with a downstream gene in the triterpene biosynthesis pathway encoding the oxidosqualene cyclase TkOSC1
expression is significantly up-regulated upon methyl jasmonate treatment
gene expression level is higher in roots as compared to the leaves, and is up-regulated upon YEC Ag+ treatment
infectionn of the plants with Fusarium oxysporum induces the squalene synthase expression
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