Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.1.3.3: ornithine carbamoyltransferase

This is an abbreviated version!
For detailed information about ornithine carbamoyltransferase, go to the full flat file.

Word Map on EC 2.1.3.3

Reaction

Carbamoyl phosphate
+
L-ornithine
=
phosphate
 +
L-citrulline

Synonyms

anabolic ornithine carbamoyltransferase, anabolic ornithine transcarbamoylase, AOTC, arcB gene product, ArgF, ArgK, aTtOTCase, carbamoyltransferase, carbamoyltransferase, ornithine, carbamylphosphate-ornithine transcarbamylase, catabolic ornithine carbamoyltransferase, catabolic ornithine transcarbamylase, citrulline phosphorylase, cOTC, L-ornithine carbamoyltransferase, L-ornithine carbamyltransferase, L-ornithine transcarbamylase, Lmo0036, MB1684, Mtb OTC, OCT, ornithine carbamoyltransferase, ornithine carbamoytransferase, ornithine carbamyl transferase, ornithine carbamyltransferase, ornithine transcarbamoylase, ornithine transcarbamylase, ornithine transcarbamylase 3, OTC, otcase, ROTCase

ECTree

     2 Transferases
         2.1 Transferring one-carbon groups
             2.1.3 Carboxy- and carbamoyltransferases
                2.1.3.3 ornithine carbamoyltransferase

pH Range

pH Range on EC 2.1.3.3 - ornithine carbamoyltransferase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
pH RANGE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4 - 11
-
activity range, anabolic and catabolic reactions
6 - 7.2
-
at 10 mM carbamoyl phosphate, sharp decrease in activity above
6 - 8.3
-
approx. 50% of maximal activity at pH 6.0
6.7 - 8.5
-
approx. 50% of maximal activity at pH 6.7 and 8.5, triethanolamine/acetate buffer
6.8 - 8.5
-
approx. 85% of maximal activity at pH 6.8, approx. 25% of maximal activity at pH 8.5
7 - 10
-
sharp decrease in activity below pH 9.0
7 - 9
-
50% of maximal activity at pH 9.0, 70% at pH 7.0
7.2 - 8.3
-
71% of maximal activity at pH 7.2, 94% of maximal activity at pH 8.3, HEPES/NaOH buffer
7.5 - 10
-
nearly constant activity in this range, half-maximal activity at pH 7.0, negliable activity at pH 6.0
7.5 - 9
-
approx. 50% of maximal activity at pH 9.0