1.7.1.16: nitrobenzene nitroreductase

This is an abbreviated version!
For detailed information about nitrobenzene nitroreductase, go to the full flat file.

Word Map on EC 1.7.1.16

Reaction

N-phenylhydroxylamine
+ 2 NADP+ +
H2O
=
nitrobenzene
+ 2 NADPH + 2 H+

Synonyms

cnbA, NbzA, NfsB, Oxygen-insensitive NAD(P)H nitroreductase

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.16 nitrobenzene nitroreductase

Crystallization

Crystallization on EC 1.7.1.16 - nitrobenzene nitroreductase

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CRYSTALLIZATION (Commentary)
ORGANISM
UNIPROT
LITERATURE
molecular dynamics simulation of free enzyme in oxidized form, fully reduced enzyme with benzoate inhibitor and fully reduced enzyme with nitrobenzene. The complexed nitroreductase becomes more flexible overall upon complexation, particularly helix H6, in the vicinity of the binding site. Five regions which are highly conserved within the flavin mononucleotide (FMN) binding site are identified