1.7.1.16: nitrobenzene nitroreductase

This is an abbreviated version!
For detailed information about nitrobenzene nitroreductase, go to the full flat file.

Word Map on EC 1.7.1.16

Reaction

N-phenylhydroxylamine
+ 2 NADP+ +
H2O
=
nitrobenzene
+ 2 NADPH + 2 H+

Synonyms

cnbA, NbzA, NfsB, Oxygen-insensitive NAD(P)H nitroreductase

ECTree

     1 Oxidoreductases
         1.7 Acting on other nitrogenous compounds as donors
             1.7.1 With NAD+ or NADP+ as acceptor
                1.7.1.16 nitrobenzene nitroreductase

Systematic Name

Systematic Name on EC 1.7.1.16 - nitrobenzene nitroreductase

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SYSTEMATIC NAME
IUBMB Comments
N-phenylhydroxylamine:NADP+ oxidoreductase
Contains FMN. The enzyme, characterized from Pseudomonas species, catalyses two successive reductions of nitrobenzene, via a nitrosobenzene intermediate. It is also active on 1-chloro-4-nitrobenzene.