1.4.3.20: L-lysine 6-oxidase

This is an abbreviated version!
For detailed information about L-lysine 6-oxidase, go to the full flat file.

Word Map on EC 1.4.3.20

Reaction

L-lysine
+
O2
+
H2O
=
(S)-2-amino-6-oxohexanoate
+
H2O2
+
NH3

Synonyms

ALPP, epsilon-lysine oxidase, L-lysine epsilon-oxidase, L-lysine-epsilon oxidase, L-lysine-epsilon-oxidase, Lod, LodA, lysine-epsilon oxidase, lysine-epsilon-oxidase, marinocine, marinocine antimicrobial protein

ECTree

     1 Oxidoreductases
         1.4 Acting on the CH-NH2 group of donors
             1.4.3 With oxygen as acceptor
                1.4.3.20 L-lysine 6-oxidase

Reaction

Reaction on EC 1.4.3.20 - L-lysine 6-oxidase

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REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-lysine + O2 + H2O = (S)-2-amino-6-oxohexanoate + H2O2 + NH3
show the reaction diagram
Differs from EC 1.4.3.13, protein-lysine 6-oxidase, by using free L-lysine rather than the protein-bound form. 2-N-Acetyl-L-lysine is also a substrate, but 6-N-acetyl-L-lysine, which has an acetyl group at position 6, is not a substrate. Also acts on L-ornithine, D-lysine and 4-hydroxy-L-lysine, but more slowly. The amines cadaverine and putrescine are not substrates
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