1.2.1.20: glutarate-semialdehyde dehydrogenase
This is an abbreviated version!
For detailed information about glutarate-semialdehyde dehydrogenase, go to the full flat file.
Word Map on EC 1.2.1.20
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1.2.1.20
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l-lysine
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5-aminovalerate
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putida
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transaminase
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fed-batch
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2-monooxygenase
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nylon
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corynebacterium
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glutamicum
- 1.2.1.20
- l-lysine
- 5-aminovalerate
- putida
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transaminase
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fed-batch
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2-monooxygenase
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nylon
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corynebacterium
- glutamicum
Reaction
Synonyms
davD, davDT davDT, dehydrogenase, glutarate semialdehyde, glutarate dialdehyde dehydrogenase, glutarate semialdehyde dehydrogenase, GSA dehydrogenase
ECTree
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Substrates Products
Substrates Products on EC 1.2.1.20 - glutarate-semialdehyde dehydrogenase
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REACTION DIAGRAM
2-hydroxybutyraldehyde + NAD+ + H2O
2-hydroxybutanoate + NADH
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low activity
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-
?
5-hydroxyvaleraldehyde + NAD+ + H2O
5-hydroxypentanoate + NADH + H+
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low activity
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-
?
glutaraldehyde + NAD+ + H2O
glutarate semialdehyde + NADH
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low activity
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-
?
5-oxopentanoate + NADP+ + H2O
glutarate + NADPH + H+
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-
-
?
5-oxopentanoate + NADP+ + H2O
glutarate + NADPH + H+
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-
-
?
5-oxopentanoate + NADP+ + H2O
glutarate + NADPH + H+
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-
-
?
glutarate semialdehyde + NAD+ + H2O
glutarate + NADH
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degradation of pyridine
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-
?
glutarate semialdehyde + NAD+ + H2O
glutarate + NADH
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-
-
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?
glutarate semialdehyde + NAD+ + H2O
glutarate + NADH
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inducible enzyme, the best inducer is delta-aminovalerate
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-
?
glutarate semialdehyde + NAD+ + H2O
glutarate + NADH
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constitutive levels of the enzyme are produced under all growth conditions. Growth on Lys leads to specific activity levels 2-3fold higher than growth on other amino acids
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-
?
glutarate semialdehyde + NAD+ + H2O
glutarate + NADH
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enzyme catalyzes the last step in the conversion of L-lysine to glutarate
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-
?
glutarate + NADH + 2 H+
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-
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?
glutarate semialdehyde + NAD+ + H2O
glutarate + NADH + 2 H+
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-
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?
glutarate + NADPH
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NAD+ is a better coenzyme than NADP+
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-
?
glutarate semialdehyde + NADP+ + H2O
glutarate + NADPH
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5% of the activity with NAD+
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-
?
glutarate semialdehyde + NADP+ + H2O
glutaric acid + NADPH + H+
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-
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?