1.2.1.17: glyoxylate dehydrogenase (acylating)

This is an abbreviated version!
For detailed information about glyoxylate dehydrogenase (acylating), go to the full flat file.

Reaction

glyoxylate
+
CoA
+
NADP+
=
oxalyl-CoA
+
NADPH
+
H+

Synonyms

acylating glyoxylate dehydrogenase, AGODH, glyoxylate-NADP+ oxidoreductase, oxalyl-CoA reductase

ECTree

     1 Oxidoreductases
         1.2 Acting on the aldehyde or oxo group of donors
             1.2.1 With NAD+ or NADP+ as acceptor
                1.2.1.17 glyoxylate dehydrogenase (acylating)

Natural Substrates Products

Natural Substrates Products on EC 1.2.1.17 - glyoxylate dehydrogenase (acylating)

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
glyoxylate + CoA + NADP+
oxalyl-CoA + NADPH
show the reaction diagram
glyoxylate + CoA + NADP+
oxalyl-CoA + NADPH + H+
show the reaction diagram
-
-
-
-
r
additional information
?
-
-
modified TCA cycle with diminished efficacy in NADH production and decreased CO2-evolving capacity, orchestrates the synthesis of oxalate, NADPH and ATP, ingredients pivotal to the survival in an aluminium environment
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-
?