1.14.12.14: 2-aminobenzenesulfonate 2,3-dioxygenase
This is an abbreviated version!
For detailed information about 2-aminobenzenesulfonate 2,3-dioxygenase, go to the full flat file.
Reaction
Synonyms
2-Aminobenzenesulfonate dioxygenase, 2-Aminosulfobenzene 2,3-dioxygenase, 2AS dioxygenase, ABS-dioxygenase, ABSDOS, Oxygenase, 2-aminobenzenesulfonate di-
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Natural Substrates Products
Natural Substrates Products on EC 1.14.12.14 - 2-aminobenzenesulfonate 2,3-dioxygenase
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REACTION DIAGRAM
2-aminobenzenesulfonate + NADH + H+ + O2
2,3-dihydroxybenzenesulfonate + NH3 + NAD+
2-aminobenzenesulfonate is used in the manufacture of dyes and pharmaceuticals, and, typical of xenobiotic aryl-sulfonates. The compound is degraded in few native environments, e.g. by Alcaligenes sp. strain O-1, the overall degradative process for ABS in strain O-1 is complex, overview. The pathway shows both split operons and dispersed pathway genes, and no transcriptional regulator
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2-aminobenzenesulfonate + NADH + O2
3-sulfocatechol + NH3 + NAD+
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enables utilization of 2-aminobenzenesulfonate as sole carbon and energy source
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initial step in degradation of of 2-aminobenzenesulfonate
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2-aminobenzenesulfonate + NADH + H+ + O2
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initial step in degradation of of 2-aminobenzenesulfonate
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