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1.14.12.1: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

This is an abbreviated version!
For detailed information about anthranilate 1,2-dioxygenase (deaminating, decarboxylating), go to the full flat file.

Wordmap for 1.14.12.1

Word Map on EC 1.14.12.1 Wordmap for 1.14.12.1

Reaction

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anthranilate
+
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NAD(P)H
+
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H+
+
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O2
=
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catechol
+
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CO2
+
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NAD(P)+
+
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NH3

Synonyms

AntDO, anthranilate hydroxylase, anthranilic acid hydroxylase, anthranilic hydroxylase, two-component anthranilate 1,2-dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                EC 1.14.12.11.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

Substrates Products

Substrates Products on EC 1.14.12.1 - anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

for references in articles please use BRENDA:EC1.14.12.1

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,3-dihydroxybenzoic acid + NAD(P)H + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
anthranilate + NADPH + H+ + O2
catechol + CO2 + NADP+ + NH3
show the reaction diagram
-
-
-
-
?
anthranilic acid + alanine + O2
?
show the reaction diagram
anthranilic acid + alanine + O2
catechol + CO2 + NH3 + ?
show the reaction diagram
anthranilic acid + NAD(P)H + O2 + H2O
catechol + CO2 + NAD(P)+ + NH3
show the reaction diagram
anthranilic acid + NADH + O2 + H2O
catechol + CO2 + NAD+ + NH3
show the reaction diagram
benzoate + NAD(P)H + O2 + H2O
benzoate dihydrodiol + ?
show the reaction diagram
catechol + O2 + NAD(P)H + H2O
?
show the reaction diagram
-
-
-
-
?
protocatechuic acid + NAD(P)H + O2 + H2O
?
show the reaction diagram
-
-
-
-
?
salicylic acid + NAD(P)H + O2 + H2O
?
show the reaction diagram
-
-
-
?
additional information
?
-
-
salicylic acid and o-aminophenol are no substrates
-
-
?