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1.14.12.1: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

This is an abbreviated version!
For detailed information about anthranilate 1,2-dioxygenase (deaminating, decarboxylating), go to the full flat file.

Wordmap for 1.14.12.1

Word Map on EC 1.14.12.1 Wordmap for 1.14.12.1

Reaction

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anthranilate
+
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NAD(P)H
+
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H+
+
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O2
=
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catechol
+
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CO2
+
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NAD(P)+
+
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NH3

Synonyms

AntDO, anthranilate hydroxylase, anthranilic acid hydroxylase, anthranilic hydroxylase, two-component anthranilate 1,2-dioxygenase

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into the other donor
                EC 1.14.12.11.14.12.1 anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

Natural Substrates Products

Natural Substrates Products on EC 1.14.12.1 - anthranilate 1,2-dioxygenase (deaminating, decarboxylating)

for references in articles please use BRENDA:EC1.14.12.1

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
LITERATURE
COMMENTARY hide
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
anthranilate + NADPH + H+ + O2
catechol + CO2 + NADP+ + NH3
show the reaction diagram
-
Substrates: -
Products: -
?
anthranilic acid + alanine + O2
catechol + CO2 + NH3 + ?
show the reaction diagram
anthranilic acid + NAD(P)H + O2 + H2O
catechol + CO2 + NAD(P)+ + NH3
show the reaction diagram