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1.1.1.423: (1R,2S)-ephedrine 1-dehydrogenase

This is an abbreviated version!
For detailed information about (1R,2S)-ephedrine 1-dehydrogenase, go to the full flat file.

Reaction

(-)-(1R,2S)-ephedrine
+
NAD+
=
(S)-2-(methylamino)-1-phenylpropan-1-one
+
NADH
+
H+

Synonyms

EDH, ephedrine dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.423 (1R,2S)-ephedrine 1-dehydrogenase

Cofactor

Cofactor on EC 1.1.1.423 - (1R,2S)-ephedrine 1-dehydrogenase

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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
NADH
no apparent activity with NADP(H)+ and full catalytic activity with NAD(H). The preference for NADH makes the utilization of the enzyme an attractive for industrial applications, since NADH is more stable and less expensive than NADPH under operational reaction conditions