1.1.1.423: (1R,2S)-ephedrine 1-dehydrogenase

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For detailed information about (1R,2S)-ephedrine 1-dehydrogenase, go to the full flat file.

Reaction

Synonyms

EDH, ephedrine dehydrogenase

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.423 (1R,2S)-ephedrine 1-dehydrogenase

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Results	in table
1	AA Sequence
3	Application
1	Cloned(Commentary)
3	Cofactor
8	Inhibitors
8	Ki Value [mM]
16	KM Value [mM]
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
2	Organism
1	pH Optimum
2	pH Stability
1	Purification (Commentary)
1	Reaction
2	Reference
56	Substrates and Products (Substrate)
3	Subunits
4	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
2	Temperature Range [°C]
3	Temperature Stability [°C]
17	Turnover Number [1/s]

Application

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Application on EC 1.1.1.423 - (1R,2S)-ephedrine 1-dehydrogenase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

industry

Arthrobacter sp. TS-15

A0A545BBR2

the wide substrate spectrum of these dehydrogenases, combined with their regio- and enantioselectivity, suggests a high potential for the industrial production of valuable chiral compounds

752351

synthesis

2 entries

synthesis

Arthrobacter sp. TS-15

A0A545BBR2

the wide substrate spectrum of these dehydrogenases, combined with their regio- and enantioselectivity, suggests a high potential for the industrial production of valuable chiral compounds

752351

synthesis

Arthrobacter sp. TS-15

A0A545BBR2

the enzyme catalyzes the oxidation of an isomer of ephedrine and the regio- and enantioselective reduction of sterically demanding substrate 1-phenyl-1,2-propanedione to give (R)-phenylacetylcarbinol

752351