1.1.1.200: aldose-6-phosphate reductase (NADPH)

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For detailed information about aldose-6-phosphate reductase (NADPH), go to the full flat file.

Word Map on EC 1.1.1.200

1.1.1.200

sorbitol

apple

domestica

malus

starch

rosaceae

peach

adp-glucose

borkh

2.4.1.14

hexokinase

sink

invertase

greensleeves

fructokinase

pyrophosphorylase

prunus

2.7.7.27

gala

sugar-phosphates

aldo-keto

sink-source

glucitol

persica

mixed-type

Reaction

Synonyms

A6PR, A6PR1, A6PR2, A6PRase, Ald6PRase, alditol 6-phosphate:NADP 1-oxidoreductase, aldose-6-P reductase, aldose-6-phosphate reductase, aldose-6-phosphate reductase [NADPH], NADP-S6PDH, NADPH-dependent aldose 6-phosphate reductase, reductase, aldose 6-phosphate, S6PDH, sorbitol-6-phosphate dehydrogenase

ECTree

1 Oxidoreductases

1.1 Acting on the CH-OH group of donors

1.1.1 With NAD⁺ or NADP⁺ as acceptor

1.1.1.200 aldose-6-phosphate reductase (NADPH)

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Results	in table
1	Activating Compound
9	AA Sequence
1	CAS Registry Number
4	Cloned(Commentary)
14	Cofactor
6	Expression
2	General Information
1	General Stability
28	Inhibitors
5	Ki Value [mM]
12	KM Value [mM]
2	Localization
3	Metals/Ions
7	Molecular Weight [Da]
13	Natural Substrates/ Products (Substrates)
18	Organism
1	Oxidation Stability
1	Pathway
2	PDB ID
1	pH Optimum
2	pH Range
1	pI Value
5	Purification (Commentary)
1	Reaction
3	Reaction Type
16	Reference
19	Source Tissue
15	Specific Activity [micromol/min/mg]
2	Storage Stability
31	Substrates and Products (Substrate)
7	Subunits
23	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Turnover Number [1/s]

General Stability

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General Stability on EC 1.1.1.200 - aldose-6-phosphate reductase (NADPH)

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enzyme thiolation with oxidized glutathione protects the enzyme from insolubilization caused by diamide, while incubation with NADP+ completely prevents enzyme precipitation

Prunus persica

A5JUQ9

762130