EC Number   |
Reaction |
Reference |
|---|
   2.5.1.63 | S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine |
- |
- |
| 2.5.1.63 | S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine |
C-F bond formation, the enzyme catalyses an SN2 type reaction mechanism |
673043 |
| 2.5.1.63 | S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine |
reaction mechanism, inversion of configuration consistent with a SN2 reaction mechanism |
658449 |
| 2.5.1.63 | S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine |
reaction mechanism, overview |
675161 |
| 2.5.1.63 | S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine |
SN2 substitution reaction mechanism, where fluoride ion mediates a nucleophilic attack to the 5'-carbon of the ribose ring of S-adenosyl-L-methionine to give 5'-deoxy-5'-fluoroadenosine. The reaction proceeds with an inversion of configuration at the C-5'carbon |
738049 |
| 2.5.1.63 | S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine |
substrate binding structure involving F156, S158, Y177, and T80, nucleophilic substitution reaction mechanism |
660001 |
