Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

BRENDA Home
show all | hide all No of entries

Information on EC 4.1.3.39 - 4-hydroxy-2-oxovalerate aldolase

for references in articles please use BRENDA:EC4.1.3.39
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.39 4-hydroxy-2-oxovalerate aldolase
IUBMB Comments
Requires Mn2+ for maximal activity . The enzyme from the bacterium Pseudomonas putida is also stimulated by NADH . In some bacterial species the enzyme forms a bifunctional complex with EC 1.2.1.10, acetaldehyde dehydrogenase (acetylating). The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 4.1.3.43, 4-hydroxy-2-oxohexanoate aldolase [4,5].
Specify your search results
Select one or more organisms in this record: ?
Show additional data
Do not include text mining results
Include (text mining) results
Include results (AMENDA + additional results, but less precise)
Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
4-hydroxy-2-oxovalerate aldolase, 4-hydroxy-2-ketovalerate aldolase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(S)-4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate
show the reaction diagram
Select items on the left to see more content.