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Synonyms
rv0805, 2',3'-cyclic nucleotide phosphohydrolase, 2',3'-cyclic phosphodiesterase, 2',3'-cyclic nucleotide 2'-phosphodiesterase, 2',3'-camp phosphodiesterase, cyclic 2',3'-nucleotide phosphodiesterase, 2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase, yfce-c74h, 2',3'-cyclic-nucleotide 2'-phosphodiesterase, 2',3'-cyclic nucleotidase,
more
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2',3'-cAMP phosphodiesterase
-
-
2',3'-cyclic AMP 2'-phosphohydrolase
-
-
-
-
2',3'-cyclic AMP phosphodiesterase
-
-
-
-
2',3'-cyclic nucleoside monophosphate phosphodiesterase
-
-
-
-
2',3'-cyclic nucleotidase
-
-
-
-
2',3'-cyclic nucleotide 2'-phosphodiesterase
-
-
-
-
2',3'-cyclic nucleotide phosphohydrolase
-
-
-
-
2',3'-cyclic phosphodiesterase
-
-
-
-
2':3'-cyclic nucleotide phosphodiesterase:3'-nucleotidase
-
-
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-
2':3'-cyclic phosphodiesterase
-
-
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-
2,3-cyclic nucleotide phosphodiesterase
-
-
cyclic 2',3'-nucleotide phosphodiesterase
-
-
-
-
cyclic phosphodiesterase:3'-nucleotidase
-
-
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-
cyclic-2',3'-nucleotide 2'-phosphohydrolase
-
-
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-
phosphodiesterase, cyclic 2',3'-nucleotide 2'-
-
-
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-
ribonucleoside 2',3'-cyclic phosphate diesterase
-
-
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Rv0805
-
functions as a 3',5'-cyclic nucleotide phosphodiesterase but has also 2',3'-cyclic nucleotide phosphodiesterase function
YfcE-C74H
the mutant enzyme is strictly specific for 2',3'-cNMP, the C74H mutation uniquely confers a gain of function in hydrolysis of 2',3'-cAMP
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2',3'-cAMP + H2O
2'-AMP + 3'-AMP
-
-
-
?
2',3'-cAMP + H2O
3'-AMP
-
-
-
-
?
2',3'-cGMP + H2O
2'-GMP + 3'-GMP
-
-
-
?
2',3'-cGMP + H2O
3'-GMP
-
-
-
-
?
2'-AMP + H2O
adenosine + phosphate
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
3'-CMP + H2O
cytidine + phosphate
3'-GMP + H2O
guanosine + phosphate
3'-UMP + H2O
uridine + phosphate
5'-dTMP p-nitrophenyl ester
?
-
-
-
?
5'-UMP + H2O
uridine + phosphate
-
weak activity
-
-
?
ADP + H2O
AMP + phosphate
-
-
-
?
alpha-naphthyl phosphate + H2O
alpha-naphthol + phosphate
-
-
-
-
?
ATP + H2O
ADP + phosphate
-
-
-
?
bis-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
CDP + H2O
CMP + phosphate
-
-
-
?
CTP + H2O
CDP + phosphate
-
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
cyclic 2',3'-CMP + H2O
3'-CMP
cyclic 2',3'-GMP + H2O
3'-GMP
cyclic 2',3'-UMP + H2O
3'-UMP
cyclic 3',5'-AMP + H2O
3'-AMP
-
-
mixture of 3-AMP and 5-AMP in a ratio of 6:1, no further hydrolysis to nucleoside and phosphate
?
cyclic 3',5'-AMP + H2O
5'-AMP
cyclic 3',5'-CMP + H2O
3'-CMP
-
-
mixture of 3-CMP and 5-CMP in a ratio of 6:1, no further hydrolysis to nucleoside and phosphate
?
cyclic 3',5'-GMP + H2O
3'-GMP
-
-
mixture of 3-GMP and 5-GMP in a ratio of 6:1, no further hydrolysis to nucleoside and phosphate
?
cyclic 3',5'-GMP + H2O
5'-GMP
cyclic 3',5'-UMP + H2O
3'-UMP
-
-
mixture of 3-UMP and 5-UMP in a ratio of 6:1, no further hydrolysis to nucleoside and phosphate
?
cyclic 3',5'-UMP + H2O
5'-UMP
di(p-nitrophenyl) phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
diphosphate + H2O
2 phosphate
NADP+ + H2O
NAD+ + phosphate
-
-
-
?
nucleoside 2',3'-cyclic phosphate + H2O
nucleoside 3'-phosphate
nucleoside 3',5'-cyclic phosphate + H2O
nucleoside 3'-phosphate
-
no apparent base specificity, 2fold higher specific activity with nucleoside 2',3'-cyclic phosphate than with the 3',5'-cyclic isomers
mixture of nucleoside 3'-phosphate and nucleoside 5'-phosphate in a ratio of 6:1, no further hydrolysis to nucleoside and phosphate
?
p-nitrophenyl phenylphosphonate + H2O
?
-
-
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
p-nitrophenyl phosphorylcholine + H2O
?
-
-
?
thymidine p-nitrophenyl phosphate + H2O
thymidine + p-nitrophenyl phosphate
-
-
-
-
?
additional information
?
-
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-AMP + H2O
adenosine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-CMP + H2O
cytidine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-GMP + H2O
guanosine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
3'-UMP + H2O
uridine + phosphate
-
-
-
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?
3'-UMP + H2O
uridine + phosphate
-
-
-
-
?
bis-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
?
bis-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
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-
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
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-
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
YfcE-C74H cleaves exclusively the P-O2' bond of 2',3'-cAMP
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
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?
cyclic 2',3'-AMP + H2O
3'-AMP
-
-
the only major reaction product
?
cyclic 2',3'-AMP + H2O
3'-AMP
-
-
the only major reaction product
?
cyclic 2',3'-AMP + H2O
3'-AMP
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-
formation of adenosine without accumulation of 3'-AMP
?
cyclic 2',3'-AMP + H2O
3'-AMP
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-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
-
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
-
Rv0805 is 150fold more active in hydrolyzing 2',3'-cAMP than 3',5'-cAMP, the enzyme hydrolyzes either P-O2' or P-O3' bonds to yield a mixture of 3'-AMP and 2'-AMP products, with a bias toward 3'-AMP
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
-
-
-
-
r
cyclic 2',3'-AMP + H2O
3'-AMP
-
-
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
-
-
-
-
?
cyclic 2',3'-AMP + H2O
3'-AMP
-
-
only product
?
cyclic 2',3'-AMP + H2O
3'-AMP
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
the only major reaction product
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
the only major reaction product
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
only product
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
-
-
?
cyclic 2',3'-CMP + H2O
3'-CMP
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
the only major reaction product
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
the only major reaction product
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
only product
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
-
-
?
cyclic 2',3'-GMP + H2O
3'-GMP
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
the only major reaction product
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
the only major reaction product
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
only product
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
-
-
?
cyclic 2',3'-UMP + H2O
3'-UMP
-
-
?
cyclic 3',5'-AMP + H2O
5'-AMP
-
at 9.1% of the activity with 2',3'-cyclic AMP
-
-
?
cyclic 3',5'-AMP + H2O
5'-AMP
weak activity
-
-
?
cyclic 3',5'-AMP + H2O
5'-AMP
-
at about 50% of the activity with 2',3'-AMP
-
?
cyclic 3',5'-AMP + H2O
5'-AMP
-
at about 50% of the activity with 2',3'-AMP
-
?
cyclic 3',5'-AMP + H2O
5'-AMP
-
weak activity, Rv0805 is 150fold more active in hydrolyzing 2',3'-cAMP than 3',5'-cAMP
-
-
?
cyclic 3',5'-GMP + H2O
5'-GMP
-
at 9.2% of the activity with 3',5'-cyclic AMP
-
?
cyclic 3',5'-GMP + H2O
5'-GMP
weak activity
-
-
?
cyclic 3',5'-GMP + H2O
5'-GMP
-
at about 50% of the activity with 2',3'-GMP
-
?
cyclic 3',5'-GMP + H2O
5'-GMP
-
at about 50% of the activity with 2',3'-GMP
-
?
cyclic 3',5'-GMP + H2O
5'-GMP
-
weak activity
-
-
?
cyclic 3',5'-UMP + H2O
5'-UMP
weak activity
-
-
?
cyclic 3',5'-UMP + H2O
5'-UMP
-
weak activity
-
-
?
di(p-nitrophenyl) phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
synthetic substrate
-
?
di(p-nitrophenyl) phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
at 50% of the activity with cyclic 2',3'-UMP
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
at 50% of the activity with cyclic 2',3'-UMP
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
di-p-nitrophenyl phosphate + H2O
p-nitrophenol + p-nitrophenyl phosphate
-
-
-
-
?
diphosphate + H2O
2 phosphate
-
-
-
?
diphosphate + H2O
2 phosphate
-
-
-
-
?
nucleoside 2',3'-cyclic phosphate + H2O
nucleoside 3'-phosphate
-
-
-
?
nucleoside 2',3'-cyclic phosphate + H2O
nucleoside 3'-phosphate
-
-
-
-
?
nucleoside 2',3'-cyclic phosphate + H2O
nucleoside 3'-phosphate
-
no apparent base specificity, 2fold higher specific activity with nucleoside 2',3'-cyclic phosphate than with the 3',5'-cyclic isomers
no further hydrolysis to nucleoside and phosphate
?
nucleoside 2',3'-cyclic phosphate + H2O
nucleoside 3'-phosphate
-
RNA degradation, enzyme functions as an accessory ribonucleolytic activity that effectively hydrolyzes the primary products of RNase LE, a phosphate starvation-inducible ribonuclease generating 2,3-cyclic nucleoside monophosphates, to substrates for phosphate starvation-inducible phosphomonoesterases
-
?
nucleoside 2',3'-cyclic phosphate + H2O
nucleoside 3'-phosphate
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
weak activity
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
-
-
-
?
p-nitrophenyl phosphate + H2O
p-nitrophenol + phosphate
-
-
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
YfcE-C74H has no detectable ability to hydrolyze phosphomonoester substrates 5'-AMP, 3'-AMP, or 2'-AMP
-
-
?
additional information
?
-
-
YfcE-C74H has no detectable ability to hydrolyze phosphomonoester substrates 5'-AMP, 3'-AMP, or 2'-AMP
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
not: 3,5-nucleoside monophosphates, nucleoside 5-, 3- or 2-monophosphates, tRNA, polyU
-
?
additional information
?
-
-
not: 3,5-nucleoside monophosphates, nucleoside 5-, 3- or 2-monophosphates, tRNA, polyU
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
higher activity towards 2',3'-cyclic nucleotides than towards 3',5'-cyclic nucleotides
-
-
?
additional information
?
-
-
higher activity towards 2',3'-cyclic nucleotides than towards 3',5'-cyclic nucleotides
-
-
?
additional information
?
-
-
the enzyme does not have a preference for 2',3'-cAMP versus 2',3'-cGMP
-
-
?
additional information
?
-
-
PdeB also shows high phosphomonoesterase activity against 5'-UMP, 3'-AMP, 3'-GMP, and low activity against 5'-dAMP
-
-
?
additional information
?
-
-
the enzyme shows no activity toward 2'-AMP and 2'-GMP, 3',5'-cGMP is either not hydrolysed or is cleaved very slowly by PdeB
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
-
-
-
-
?
additional information
?
-
-
3'-nucleotidase and 5'-nucleotidase activity resides in the same protein
-
-
?
additional information
?
-
bifunctional enzyme with 2,3-cyclic phosphodiesterase and 3-nucleotidase activity
-
?
additional information
?
-
-
bifunctional enzyme with 2,3-cyclic phosphodiesterase and 3-nucleotidase activity
-
?
additional information
?
-
CpdB may be a fitness factor involved in the salvage of nucleotides from the environment
-
?
additional information
?
-
-
CpdB may be a fitness factor involved in the salvage of nucleotides from the environment
-
?
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KCN
-
slight activation of cyclic phosphodiesterase
Ca2+
-
activates
Ca2+
-
stimulates cleavage of di-p-nitrophenyl phosphate
Co2+
-
no activation
Co2+
-
10 mM, 2-3fold stimulation
Co2+
-
0.1-1 mM, 3-5fold activation
Co2+
-
stimulates cleavage of dis-p-nitrophenyl phosphate
Co2+
-
PdeB is stimulated about 2fold by 0.05 mM Co2+, at pH 8.0 in 50 mM Tris-HCl buffer with cyclic 3',5'-AMP as substrate
Mg2+
-
activates
Mg2+
-
1-10 mM, slight increase of activity
Mg2+
activataes with 2'-AMP, KD: 0.24 +/- 0.1 mM
Mg2+
activates with 2',3'-cAMP, KD: 0.49 +/- 0.1 mM
Mg2+
activates with ATP, KD ~ 0.1 mM
Mn2+
-
increases activity with bi-p-nitrophenyl phosphate, maximal activity at 10 mM
Mn2+
-
10 mM, 2-3fold stimulation
Mn2+
-
PdeB is stimulated about 2fold by 0.05 mM Mn2+, at pH 8.0 in 50 mM Tris-HCl buffer with cyclic 3',5'-AMP as substrate
Mn2+
-
0.2 mM, 6-10% stimulation
Ni2+
activates with diphosphate, KD: 1.06 +/- 0.1 uM
Ni2+
activates with p-nitrophenyl phosphate, KD: 6.0 +/- 0.7 uM
additional information
-
no requirement for metal ions
additional information
-
no requirement for metal ions
additional information
-
enzymatic activity is not stimulated by Ca2+, Mg2+, Fe2+, Fe3+, and Zn2+
additional information
-
independent of divalent metal ions, e.g. Mg2+, Mn2+, Ca2+ and Co2+, all at 5mM
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2'-AMP
-
2',3'-cyclic nucleotide phosphodiesterase activity
3',5'-cAMP
-
2',3'-cyclic nucleotide phosphodiesterase activity
3'-AMP
-
cleavage of 2',3'-cyclic nucleotides
5'-ADP
-
2',3'-cyclic nucleotide phosphodiesterase activity
5'-AMP
-
2',3'-cyclic nucleotide phosphodiesterase activity
5'-ATP
-
2',3'-cyclic nucleotide phosphodiesterase activity
5'-CMP
-
2',3'-cyclic nucleotide phosphodiesterase activity
5'-GMP
-
2',3'-cyclic nucleotide phosphodiesterase activity
5'-UMP
-
2',3'-cyclic nucleotide phosphodiesterase activity
adenosine
-
2',3'-cyclic nucleotide phosphodiesterase activity
Br-
-
activates hydrolysis of 3'-nucleotides and di-p-dinitrophenyl phosphate
Calmodulin
-
stimulates activity towards 2',3'-cyclic nucleotides and 3',5'-cyclic nucleotides
CH3COO-
-
activates hydrolysis of 3'-nucleotides and di-p-dinitrophenyl phosphate
cytidine
-
2',3'-cyclic nucleotide phosphodiesterase activity
guanosine
-
2',3'-cyclic nucleotide phosphodiesterase activity
HCOO-
-
activates hydrolysis of 3'-nucleotides and di-p-dinitrophenyl phosphate
I-
-
activates hydrolysis of 3'-nucleotides and di-p-dinitrophenyl phosphate
NO3-
-
activates hydrolysis of 3'-nucleotides and di-p-dinitrophenyl phosphate
uridine
-
2',3'-cyclic nucleotide phosphodiesterase activity
additional information
-
monovalent cations activate in the order of decreasing effectiveness: Cl-, Br-/I-, NO3-, HCOO-, CH3COO-
-
Cl-
-
activates 3'-nucleotidase activity
Cl-
-
activates hydrolysis of 3'-nucleotides and di-p-dinitrophenyl phosphate
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