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2-aminoadipate + pyruvate
2-oxoadipate + L-alanine
2-oxo-3-methylvalerate + L-glutamate
2-amino-3-methylpentanoate + 2-oxoglutarate
-
-
-
-
?
2-oxoadipate + L-glutamate
L-2-aminoadipate + 2-oxoglutarate
2-oxoglutarate + L-2-aminoadipate
2-oxoadipate + L-glutamate
-
-
-
-
r
2-oxoglutarate + L-tyrosine
L-glutamate + 4-hydroxyphenylpyruvate
-
-
-
-
r
2-oxoisocaproate + L-glutamate
?
-
-
-
?
2-oxoisocaproate + L-glutamate
L-leucine + 2-oxoglutarate
-
-
-
-
?
2-oxoisovalerate + L-glutamate
L-valine + 2-oxoglutarate
-
-
-
-
?
3,5-di-iodotyrosine + 2-oxoglutarate
3,5-diiodophenylpyruvate + L-glutamate
DL-2-aminopimelic acid + 2-oxoglutarate
2-oxoadipate + L-glutamate
kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
L-2-aminoadipate + 4-hydroxyphenylpyruvate
2-oxoadipate + L-tyrosine
-
-
-
-
?
L-glutamate + 4-hydroxyphenylpyruvate
2-oxoglutarate + L-tyrosine
-
-
-
-
r
L-histidine + 2-oxoglutarate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-glutamate
L-histidine + pyruvate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-alanine
L-leucine + 2-oxoglutarate
4-methyl-2-oxopentanoate + L-glutamate
L-norleucine + 2-oxoglutarate
2-oxohexanoate + L-glutamate
L-phenylalanine + 2-oxoglutarate
phenylpyruvate + L-glutamate
-
-
-
-
?
L-tryptophan + 2-oxoglutarate
3-indole-2-oxopropanoate + L-glutamate
-
-
-
-
?
oxaloacetate + L-glutamate
2-aminosuccinate + 2-oxoglutarate
-
-
-
-
?
phenylpyruvate + 2-aminoadipate
L-phenylalanine + 2-oxoglutarate
-
-
-
-
?
pyruvate + L-glutamate
L-alanine + 2-oxoglutarate
-
-
-
-
?
additional information
?
-
2-aminoadipate + pyruvate
2-oxoadipate + L-alanine
-
-
-
-
r
2-aminoadipate + pyruvate
2-oxoadipate + L-alanine
-
-
-
-
r
2-aminoadipate + pyruvate
2-oxoadipate + L-alanine
-
-
-
-
?
2-oxoadipate + L-glutamate
L-2-aminoadipate + 2-oxoglutarate
-
-
-
r
2-oxoadipate + L-glutamate
L-2-aminoadipate + 2-oxoglutarate
-
-
-
-
?
3,5-di-iodotyrosine + 2-oxoglutarate
3,5-diiodophenylpyruvate + L-glutamate
-
-
-
-
r
3,5-di-iodotyrosine + 2-oxoglutarate
3,5-diiodophenylpyruvate + L-glutamate
-
-
-
-
r
DL-2-aminopimelic acid + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
-
r
DL-2-aminopimelic acid + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
-
r
kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate
-
-
-
-
ir
kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate
-
-
-
-
ir
kynurenine + 2-oxoglutarate
kynurenic acid + L-glutamate
-
-
-
ir
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
lysine catabolic pathway
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
?
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
lysine catabolic pathway
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
lysine and tryptophan metabolism
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
also transamination of methionine, 2-oxocaproic acid, phenylpyruvate and 2-oxo-4-methylthiobutyrate
-
-
?
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
lysine catabolic pathway
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
lysine catabolic pathway
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
r
L-2-aminoadipate + 2-oxoglutarate
2-oxoadipate + L-glutamate
-
-
-
?
L-histidine + 2-oxoglutarate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-glutamate
-
-
-
-
r
L-histidine + 2-oxoglutarate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-glutamate
-
-
-
-
r
L-histidine + 2-oxoglutarate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-glutamate
-
-
-
-
r
L-histidine + pyruvate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-alanine
-
-
-
-
r
L-histidine + pyruvate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-alanine
-
-
-
-
r
L-histidine + pyruvate
3-(1H-imidazol-4-yl)-2-oxopropanoate + L-alanine
-
-
-
-
r
L-leucine + 2-oxoglutarate
4-methyl-2-oxopentanoate + L-glutamate
-
-
-
-
?
L-leucine + 2-oxoglutarate
4-methyl-2-oxopentanoate + L-glutamate
-
-
-
?
L-norleucine + 2-oxoglutarate
2-oxohexanoate + L-glutamate
-
-
-
-
r
L-norleucine + 2-oxoglutarate
2-oxohexanoate + L-glutamate
-
-
-
-
r
L-norleucine + 2-oxoglutarate
2-oxohexanoate + L-glutamate
-
-
-
-
r
additional information
?
-
-
only slight activity with phenylalanine, tryptophan, tyrosine, aspartate or alanine as amino group donors, glyoxylate is no amino group acceptor
-
-
?
additional information
?
-
-
no kynurenine aminotransferase activity
-
-
?
additional information
?
-
enzyme displays aromatic and alpha-aminoadipate aminotransferase activity, ECs 2.4.1.39 and 2.4.1.57
-
-
?
additional information
?
-
-
2 isoenzymes, AadAT-I and AadAT-II, isoenzyme AadAT-II shows additional activity with tryptophan or kynurenine-2-oxoglutarate reaction, only slight activity with asparagine, alanine, arginine, ornithine, isoleucine, valine, leucine, lysine, serine, threonine, phenylalanine, tyrosine, histidine, glutamine, methionine or aspartate with 2-oxoglutarate
-
-
?
additional information
?
-
-
only slight activity with phenylalanine, tryptophan, tyrosine, aspartate or alanine as amino group donors, glyoxylate is no amino group acceptor
-
-
?
additional information
?
-
-
less than 2% activity with L-aspartate, L-alanine, L-alpha-aminobutyrate, glycine, L-valine, L-leucine, L-isoleucine, L-norvaline, L-epsilon-aminocaproate, L-threonine, L-serine, L-homoserine, L-cysteine, L-methionine, L-lysine, L-arginine, L-citrulline, L-ornithine, L-histidine, L-tyrosine, L-tryptophan, L-phenylalanine, L-proline and L-glutamate
-
-
?
additional information
?
-
-
2-aminoadipate aminotransferase and kynurenine aminotransferase, EC 2.6.1.7, activities are properties of a single protein
-
-
?
additional information
?
-
-
2-aminoadipate aminotransferase and kynurenine aminotransferase, EC 2.6.1.7, activities are properties of a single protein
-
-
?
additional information
?
-
-
2-aminoadipate aminotransferase and kynurenine aminotransferase, EC 2.6.1.7, activities are properties of a single protein
-
-
?
additional information
?
-
-
2-aminoadipate aminotransferase and kynurenine aminotransferase, EC 2.6.1.7, activities are properties of a single protein
-
-
?
additional information
?
-
-
2-aminoadipate aminotransferase and kynurenine aminotransferase, EC 2.6.1.7, activities are properties of a single protein
-
-
?
additional information
?
-
2-aminoadipate aminotransferase and kynurenine aminotransferase, EC 2.6.1.7, activities are properties of a single protein
-
-
?
additional information
?
-
-
KAT and AadAT activities are associated with 2 different proteins
-
-
?
additional information
?
-
-
KAT and AadAT activities are associated with 2 different proteins
-
-
?
additional information
?
-
-
only slight activity with phenylalanine, tryptophan, tyrosine, aspartate or alanine as amino group donors, glyoxylate is no amino group acceptor
-
-
?
additional information
?
-
-
2-aminoadipate aminotransferase and kynurenine aminotransferase, EC 2.6.1.7, activities are properties of a single protein
-
-
?
additional information
?
-
-
AAA-AT can recognize various kinds of substrates using the mobile alpha2 helix
-
-
?
additional information
?
-
negligible activity is observed for L-Asp
-
-
?
additional information
?
-
-
negligible activity is observed for L-Asp
-
-
?
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0.1483
2-oxo-3-methylvalerate
-
pH 7.5, 45°C
0.27 - 3.6
2-oxoglutarate
0.0288 - 0.43
2-oxoisocaproate
0.0133
2-oxoisovalerate
-
pH 7.5, 45°C
1.4
glutamate
-
pH 8.0, 37°C
0.02 - 20
L-2-aminoadipate
1
L-phenylalanine
-
pH 7.0, temperature not specified in the publication
0.5
L-tyrosine
-
pH 7.0, temperature not specified in the publication
0.01
2-oxoadipate
-
pH 6.5, 37°C
0.024
2-oxoadipate
-
pH 7.5, 45°C
0.1
2-oxoadipate
pH 7.0, 22°C
0.12
2-oxoadipate
-
pH 7.0, temperature not specified in the publication
1
2-oxoadipate
-
pH 8.0, 37°C isoenzyme AadAT-II
2.5
2-oxoadipate
-
pH 8.0, 37°C isoenzyme AadAT-I
0.5
2-oxoadipic acid
-
pH 7.0, 37°C
0.5
2-oxoadipic acid
-
pH 7.0, 37°C
0.27
2-oxoglutarate
wild type enzyme, using L-leucine as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.3
2-oxoglutarate
wild type enzyme, using L-2-aminoadipate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.4
2-oxoglutarate
mutant enzyme S20E, using L-leucine as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.41
2-oxoglutarate
mutant enzyme S20E, using L-2-aminoadipate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.42
2-oxoglutarate
mutant enzyme R23Q, using L-2-aminoadipate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.54
2-oxoglutarate
mutant enzyme R23A, using L-2-aminoadipate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.55
2-oxoglutarate
mutant enzyme R23Q, using L-leucine as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.61
2-oxoglutarate
mutant enzyme R23A, using L-leucine as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
1.1
2-oxoglutarate
-
pH 8.0, 37°C isoenzyme AadAT-I
3.2
2-oxoglutarate
-
pH 8.0, 37°C isoenzyme AadAT-II
3.6
2-oxoglutarate
-
pH 7.0, temperature not specified in the publication
0.0288
2-oxoisocaproate
-
pH 7.5, 45°C
0.048
2-oxoisocaproate
mutant enzyme R23A, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.05
2-oxoisocaproate
mutant enzyme S20E, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.091
2-oxoisocaproate
mutant enzyme R23Q, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.43
2-oxoisocaproate
wild type enzyme, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.02
L-2-aminoadipate
pH 7.0, 22°C
0.25
L-2-aminoadipate
-
pH 8.0, 37°C isoenzyme AadAT-II
0.81
L-2-aminoadipate
wild type enzyme, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
3.3
L-2-aminoadipate
mutant enzyme R23A, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
7
L-2-aminoadipate
mutant enzyme S20E, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
8.8
L-2-aminoadipate
-
pH 7.0, temperature not specified in the publication
11
L-2-aminoadipate
mutant enzyme R23Q, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
20
L-2-aminoadipate
-
pH 8.0, 37°C
0.46
L-glutamate
wild type enzyme, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
12.5
L-glutamate
-
pH 8.0, 37°C, isoenzyme AadAT-II
26
L-glutamate
-
pH 7.0, temperature not specified in the publication
62
L-glutamate
mutant enzyme R23Q, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
82
L-glutamate
mutant enzyme S20E, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
250
L-glutamate
mutant enzyme R23A, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
4.6
L-Glutamic acid
-
pH 7.0, 37°C
4.6
L-Glutamic acid
-
pH 7.0, 37°C
0.2
L-leucine
mutant enzyme S20E, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.39
L-leucine
mutant enzyme R23A, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.88
L-leucine
mutant enzyme R23Q, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.95
L-leucine
wild type enzyme, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
3.5
2-oxo-3-methylvalerate
-
pH 7.5, 45°C
22.3
2-oxoadipate
-
pH 7.5, 45°C
17.8
2-oxoisocaproate
-
pH 7.5, 45°C
2.1
2-oxoisovalerate
-
pH 7.5, 45°C
0.011 - 18.4
L-2-aminoadipate
8.3
L-phenylalanine
-
pH 7.0, temperature not specified in the publication
12.3
L-tyrosine
-
pH 7.0, temperature not specified in the publication
0.011
L-2-aminoadipate
mutant enzyme R23A, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.04
L-2-aminoadipate
mutant enzyme S20E, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.083
L-2-aminoadipate
mutant enzyme R23Q, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
6.7
L-2-aminoadipate
wild type enzyme, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
18.4
L-2-aminoadipate
-
pH 7.0, temperature not specified in the publication
0.23
L-glutamate
mutant enzyme R23A, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.5
L-glutamate
mutant enzyme R23Q, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
1.2
L-glutamate
mutant enzyme S20E, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
12.8
L-glutamate
-
pH 7.0, temperature not specified in the publication
16
L-glutamate
wild type enzyme, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.009
L-leucine
mutant enzyme R23A, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.023
L-leucine
mutant enzyme S20E, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.05
L-leucine
mutant enzyme R23Q, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
5.1
L-leucine
wild type enzyme, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.015 - 22
2-oxoglutarate
4.8 - 34
2-oxoisocaproate
0.0033 - 8.2
L-2-aminoadipate
0.015
2-oxoglutarate
mutant enzyme R23A, using L-leucine as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.021
2-oxoglutarate
mutant enzyme R23A, using L-2-aminoadipate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.06
2-oxoglutarate
mutant enzyme S20E, using L-leucine as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.091
2-oxoglutarate
mutant enzyme R23Q, using L-leucine as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.097
2-oxoglutarate
mutant enzyme S20E, using L-2-aminoadipate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.2
2-oxoglutarate
mutant enzyme R23Q, using L-2-aminoadipate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
19
2-oxoglutarate
wild type enzyme, using L-leucine as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
22
2-oxoglutarate
wild type enzyme, using L-2-aminoadipate as cosubstrate, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
4.8
2-oxoisocaproate
mutant enzyme R23A, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
5.5
2-oxoisocaproate
mutant enzyme R23Q, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
24
2-oxoisocaproate
mutant enzyme S20E, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
34
2-oxoisocaproate
wild type enzyme, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.0033
L-2-aminoadipate
mutant enzyme R23A, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.0057
L-2-aminoadipate
mutant enzyme S20E, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.0075
L-2-aminoadipate
mutant enzyme R23Q, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
8.2
L-2-aminoadipate
wild type enzyme, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.0009
L-glutamate
mutant enzyme R23A, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.0081
L-glutamate
mutant enzyme R23Q, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.014
L-glutamate
mutant enzyme S20E, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
37
L-glutamate
wild type enzyme, using 2-oxoisocaproate as cosubstrate, in 50 mM HEPESNaOH buffer, pH 8.0, containing 50 mM NH4Cl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.023
L-leucine
mutant enzyme R23A, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.057
L-leucine
mutant enzyme R23Q, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
0.12
L-leucine
mutant enzyme S20E, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
5.4
L-leucine
wild type enzyme, in 50 mM HEPES-NaOH buffer, pH 8.0, 50 mM KCl, 0.15 mM pyridoxal 5'-phosphate, at 45°C
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Hartline, R.A.
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47
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1993
Homo sapiens
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Homo sapiens, Homo sapiens (Q8N5Z0)
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Thermus thermophilus
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75
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Thermus thermophilus
brenda
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Thermus thermophilus (Q72LL6), Thermus thermophilus
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Homo sapiens (Q8N5Z0), Homo sapiens
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Structure, expression, and function of kynurenine aminotransferases in human and rodent brains
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2010
Mus musculus, Rattus norvegicus, Homo sapiens (Q8N5Z0)
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Characterization of two aminotransferases from Candida albicans
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2015
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