Reference on EC 1.14.11.27 - [histone H3]-dimethyl-L-lysine36 demethylase
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Tsukada, Y.; Fang, J.; Erdjument-Bromage, H.; Warren, M.E.; Borchers, C.H.; Tempst, P.; Zhang, Y.
Histone demethylation by a family of JmjC domain-containing proteins
Nature
439
811-816
2006
Saccharomyces cerevisiae, Homo sapiens
Fang, J.; Hogan, G.J.; Liang, G.; Lieb, J.D.; Zhang, Y.
The Saccharomyces cerevisiae histone demethylase Jhd1 fine-tunes the distribution of H3K36me2
Mol. Cell. Biol.
27
5055-5065
2007
Saccharomyces cerevisiae (P40034)
Pfau, R.; Tzatsos, A.; Kampranis, S.C.; Serebrennikova, O.B.; Bear, S.E.; Tsichlis, P.N.
Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process
Proc. Natl. Acad. Sci. USA
105
1907-1912
2008
Rattus norvegicus
Lagarou, A.; Mohd-Sarip, A.; Moshkin, Y.; Chalkley, G.; Bezstarosti, K.; Demmers, J.; Verrijzer, C.
dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing
Genes Dev.
22
2799-2810
2008
Drosophila melanogaster (Q9VHH9)
Cui, L.; Fan, Q.; Cui, L.; Miao, J.
Histone lysine methyltransferases and demethylases in Plasmodium falciparum
Int. J. Parasitol.
38
1083-1097
2008
Plasmodium falciparum
He, J.; Kallin, E.M.; Tsukada, Y.; Zhang, Y.
The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15(Ink4b)
Nat. Struct. Mol. Biol.
15
1169-1175
2008
Mus musculus (Q6P1G2), Mus musculus
Lan, F.; Shi, Y.
Epigenetic regulation: methylation of histone and non-histone proteins
Sci. China C Life Sci.
52
311-322
2009
Drosophila melanogaster
Peng, Y.B.; Fan, B.; Han, X.L.; Xu, X.W.; Rothschild, M.F.; Yerle, M.; Liu, B.
Molecular characterization of the porcine JHDM1A gene associated with average daily gain: evaluation its role in skeletal muscle development and growth
Mol. Biol. Rep.
38
4697-4704
2011
Sus scrofa
He, J.; Nguyen, A.T.; Zhang, Y.
KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia
Blood
117
3869-3880
2011
Homo sapiens
Ishimura, A.; Minehata, K.; Terashima, M.; Kondoh, G.; Hara, T.; Suzuki, T.
Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression
Development
139
749-759
2012
Mus musculus
Hillringhaus, L.; Yue, W.W.; Rose, N.R.; Ng, S.S.; Gileadi, C.; Loenarz, C.; Bello, S.H.; Bray, J.E.; Schofield, C.J.; Oppermann, U.
Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family
J. Biol. Chem.
286
41616-41625
2011
Homo sapiens, Homo sapiens (O75164), Homo sapiens (Q9H3R0)
Pan, D.; Mao, C.; Zou, T.; Yao, A.Y.; Cooper, M.P.; Boyartchuk, V.; Wang, Y.X.
The histone demethylase Jhdm1a regulates hepatic gluconeogenesis
PLoS Genet.
8
e1002761
2012
Homo sapiens, Mus musculus, Mus musculus C57/BL6J
Fnu, S.; Williamson, E.; De Haro, L.; Brenneman, M.; Wray, J.; Shaheen, M.; Radhakrishnan, K.; Lee, S.; Nickoloff, J.; Hromas, R.
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining
Proc. Natl. Acad. Sci. USA
108
540-545
2011
Homo sapiens
Ryu, H.; Ahn, S.
Yeast histone H3 lysine 4 demethylase Jhd2 regulates mitotic ribosomal DNA condensation
BMC Biol.
12
75
2014
Saccharomyces cerevisiae (P40034)
Kupershmit, I.; Khoury-Haddad, H.; Awwad, S.W.; Guttmann-Raviv, N.; Ayoub, N.
KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis
Nucleic Acids Res.
42
6168-6182
2014
Homo sapiens (O75164), Homo sapiens (O94953), Homo sapiens (Q6B0I6), Homo sapiens (Q9H3R0), Homo sapiens
Liu, H.; Wang, C.; Lee, S.; Deng, Y.; Wither, M.; Oh, S.; Ning, F.; Dege, C.; Zhang, Q.; Liu, X.; Johnson, A.M.; Zang, J.; Chen, Z.; Janknecht, R.; Hansen, K.; Marrack, P.; Li, C.Y.; Kappler, J.W.; Hagman, J.; Zhang, G.
Clipping of arginine-methylated histone tails by JMJD5 and JMJD7
Proc. Natl. Acad. Sci. USA
114
E7717-E7726
2017
Homo sapiens (P0C870), Homo sapiens (Q8N371)
Polytarchou, C.; Pfau, R.; Hatziapostolou, M.; Tsichlis, P.
The JmjC domain histone demethylase Ndy1 regulates redox homeostasis and protects cells from oxidative stress
Mol. Cell. Biol.
28
7451-7464
2008
Mus musculus
Ding, G.; Xu, X.; Li, D.; Chen, Y.; Wang, W.; Ping, D.; Jia, S.; Cao, L.
Fisetin inhibits proliferation of pancreatic adenocarcinoma by inducing DNA damage via RFXAP/KDM4A-dependent histone H3K36 demethylation
Cell Death Dis.
11
893
2020
Homo sapiens (O75164)
Zhou, J.; Wang, F.; Xu, C.; Zhou, Z.; Zhang, W.
The histone demethylase JMJD2A regulates the expression of BDNF and mediates neuropathic pain in mice
Exp. Cell Res.
361
155-162
2017
Homo sapiens (O75164), Mus musculus (Q8BW72), Mus musculus
Kwon, D.H.; Kang, J.Y.; Joung, H.; Kim, J.Y.; Jeong, A.; Min, H.K.; Shin, S.; Lee, Y.G.; Kim, Y.K.; Seo, S.B.; Kook, H.
SRF is a nonhistone methylation target of KDM2B and SET7 in the regulation of skeletal muscle differentiation
Exp. Mol. Med.
53
250-263
2021
Homo sapiens (Q8NHM5)
Separovich, R.J.; Wong, M.W.M.; Bartolec, T.K.; Hamey, J.J.; Wilkins, M.R.
Site-specific phosphorylation of histone H3K36 methyltransferase Set2p and demethylase Jhd1p is required for stress responses in Saccharomyces cerevisiae
J. Mol. Biol.
434
167500
2022
Saccharomyces cerevisiae (P40034)
Staberg, M.; Rasmussen, R.D.; Michaelsen, S.R.; Pedersen, H.; Jensen, K.E.; Villingshoj, M.; Skjoth-Rasmussen, J.; Brennum, J.; Vitting-Seerup, K.; Poulsen, H.S.; Hamerlik, P.
Targeting glioma stem-like cell survival and chemoresistance through inhibition of lysine-specific histone demethylase KDM2B
Mol. Oncol.
12
406-420
2018
Homo sapiens (Q8NHM5)
Turberfield, A.H.; Kondo, T.; Nakayama, M.; Koseki, Y.; King, H.W.; Koseki, H.; Klose, R.J.
KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity
Nucleic Acids Res.
47
9005-9023
2019
Mus musculus (P59997), Mus musculus (Q6P1G2)
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