2.7.4.13: (deoxy)nucleoside-phosphate kinase
This is an abbreviated version!
For detailed information about (deoxy)nucleoside-phosphate kinase, go to the full flat file.
Word Map on EC 2.7.4.13
-
2.7.4.13
-
single-stranded
-
dihydrofolate
-
fork
-
triphosphates
-
ribonucleotide
-
viruses
-
hydroxymethylase
-
amber
- 2.7.4.13
-
single-stranded
- dihydrofolate
-
fork
- triphosphates
- ribonucleotide
- viruses
-
hydroxymethylase
-
amber
Reaction
Synonyms
AK, CK, deoxyadenylate monophosphate kinase, deoxycytidylate monophosphate kinase, deoxyguanylate monophosphate kinase, deoxynucleoside monophosphate kinase, deoxynucleoside-5'-monophosphate kinase, deoxyribonucleoside monophosphate kinase, deoxyribonucleoside monophosphokinase, deoxythymidylate monophosphate kinase, dNMP kinase, dNMPK, GK, kinase (phosphorylating), deoxynucleoside monophosphate, T5 bacteriophage dNMPK, TK
ECTree
2.7.4.13 (deoxy)nucleoside-phosphate kinaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.7.4.13 - (deoxy)nucleoside-phosphate kinase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
top
SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
ATP + 5-bromo-dUMP
ADP + 5-bromo-dUDP
Tequintavirus T5
-
phosphorylated at 45% the rate of dAMP
-
-
r
ATP + dAMP
ADP + dADP
Tequintavirus T5
-
dATP can replace ATP with less efficiency
-
r
ATP + dCMP
ADP + dCDP
Tequintavirus T5
-
phosphorylated at 30% the rate of dAMP, dATP can replace ATP
-
r
ATP + dCMP
ADP + dCDP
Tequintavirus T5
35.2% of the activity with dAMP, wild-type enzyme
-
-
?
ATP + deoxynucleoside monophosphate
ADP + deoxynucleoside diphosphate
-
key step in de novo DNA precursor biosynthesis
-
-
r
ATP + deoxynucleoside monophosphate
ADP + deoxynucleoside diphosphate
Tequintavirus T5
key step in de novo DNA precursor biosynthesis
-
-
?
ATP + deoxynucleoside phosphate
ADP + deoxynucleoside diphosphate
Tequatrovirus T4
-
enzyme induced during viral infection
-
-
?
ATP + deoxynucleoside phosphate
ADP + deoxynucleoside diphosphate
Tequintavirus T5
-
enzyme induced during viral infection
-
r
ATP + deoxynucleoside phosphate
ADP + deoxynucleoside diphosphate
Tequintavirus T5
-
enzyme induced during viral infection
-
r
ATP + dGMP
ADP + dGDP
Tequintavirus T5
49.9% of the activity with dAMP, wild-type enzyme
-
-
?
ATP + dTMP
ADP + dTDP
Tequintavirus T5
-
dATP can replace ATP with less efficiency
-
r
ATP + dTMP
ADP + dTDP
Tequintavirus T5
56.4% of the activity with dAMP, wild-type enzyme
-
-
?
additional information
?
-
Tequintavirus T5
-
very poor acceptor substrates are AMP, CMP or dUMP
-
-
?
additional information
?
-
Tequintavirus T5
-
no acceptor substrates are dIMP, deoxyxanthylate, 5-hydroxymethyldeoxycytidylate, UMP, GMP, 5-bromo-dUMP, 5-methyl-dCMP or deoxythymidine
-
-
?
additional information
?
-
Tequintavirus T5
-
no donor substrates are UTP, GTP, CTP, dTTP, dGTP or dCTP
-
-
?
