2.7.1.49: hydroxymethylpyrimidine kinase

This is an abbreviated version!
For detailed information about hydroxymethylpyrimidine kinase, go to the full flat file.

Word Map on EC 2.7.1.49

2.7.1.49

pyridoxal

2.7.1.35

thiamin

5'-phosphate

pyridoxamine

plk

tenas

thiaminase

pyridoxal-5'-phosphate

2-methyl-4-amino-5-hydroxymethylpyrimidine

synthesis

Reaction

4-Amino-5-hydroxymethyl-2-methylpyrimidine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

Synonyms

4-amino-5-hydroxymethyl-2-methyl pyrimidine kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine (phosphate) kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine kinase, 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate kinase, EC 2.7.1.14, EC 2.7.1.35, HMP kinase, HMP-P kinase, HMP/HMP phosphate kinase, HMP/HMP-P kinase, HMPK, HMPPK, HVO_2666, hydroxymethylpyrimidine kinase (phosphorylating), hydroxymethylpyrimidine phosphate kinase, More, pyridoxal kinase, SAV0580, StHMPPK, Thi20, Thi20p, THI3, ThiD, TTHA0680, TtHMPPK

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.1 Phosphotransferases with an alcohol group as acceptor

2.7.1.49 hydroxymethylpyrimidine kinase

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Results	in table
11901	AA Sequence
1	Application
1	CAS Registry Number
14	Cloned(Commentary)
5	Cofactor
2	Crystallization (Commentary)
56	General Information
1	General Stability
3	IC50 Value
7	Inhibitors
1	kcat/KM [mM/s]
2	Ki Value [mM]
25	KM Value [mM]
3	Localization
7	Metals/Ions
11	Molecular Weight [Da]
62	Natural Substrates/ Products (Substrates)
40	Organism
7	Pathway
2	PDB ID
9	pH Optimum
2	pH Range
1	pI Value
15	Protein Variants
12	Purification (Commentary)
8	Reaction
1	Reaction Type
37	Reference
4	Source Tissue
5	Specific Activity [micromol/min/mg]
4	Storage Stability
119	Substrates and Products (Substrate)
9	Subunits
113	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
5	Temperature Stability [°C]
11	Turnover Number [1/s]

Natural Substrates Products

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Natural Substrates Products on EC 2.7.1.49 - hydroxymethylpyrimidine kinase

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ATP + 2-methyl-4-amino-5-hydroxymethylpyrimidine

ADP + 2-methyl-4-amino-5-phosphomethylpyrimidine

7 entries

ATP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

ADP + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

16 entries

ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine

ADP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

30 entries

ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine

ADP + 4-amino-5-phosphomethyl-2-methylpyrimidine

3 entries

ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine

ADP + 4-amino-5-phosphonooxymethyl-2-methylpyrimidine

Saccharomyces cerevisiae

Q08224

661316, 686824

ATP + 4-amino-5-phosphomethyl-2-methylpyrimidine

ADP + 4-amino-5-diphosphomethyl-2-methylpyrimidine

3 entries

additional information

Bacillus subtilis

the enzyme has both a biosynthetic and a salvage pathway function

662007