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2.6.1.75: cysteine-conjugate transaminase

This is an abbreviated version!
For detailed information about cysteine-conjugate transaminase, go to the full flat file.

Reaction

S-(4-Bromophenyl)-L-cysteine
+
2-oxoglutarate
=
S-(4-bromophenyl)mercaptopyruvate
+
L-glutamate

Synonyms

aminotransferase, cysteine conjugate, cysteine-conjugate alpha-ketoglutarate transaminase

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.75 cysteine-conjugate transaminase

Inhibitors

Inhibitors on EC 2.6.1.75 - cysteine-conjugate transaminase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
aminooxyacetic acid
-
1 mM, complete inhibition of the three isoenzymes
EDTA
-
1 mM, 92% remaining activity
hydroxylamine
-
1 mM, complete inhibition of the three isoenzymes
KCN
-
1 mM, 38% remaining activity for CAT 1, less efficient inhibitor for CAT-IIA and CAT-IIB
MgCl2
-
1 mM, 90% remaining activity
additional information
-
iodoacetic acid and dithiothreitol, at 1 mM concentration, are poor inhibitors
-