2.6.1.75: cysteine-conjugate transaminase

This is an abbreviated version!
For detailed information about cysteine-conjugate transaminase, go to the full flat file.

Reaction

Synonyms

aminotransferase, cysteine conjugate, cysteine-conjugate alpha-ketoglutarate transaminase

ECTree

2 Transferases

2.6 Transferring nitrogenous groups

2.6.1 Transaminases

2.6.1.75 cysteine-conjugate transaminase

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Results	in table
1	Activating Compound
1	CAS Registry Number
1	Cofactor
1	General Stability
6	Inhibitors
6	KM Value [mM]
1	Localization
1	Metals/Ions
2	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
1	Organism
2	pH Optimum
1	Purification (Commentary)
1	Reaction
1	Reaction Type
1	Reference
1	Source Tissue
3	Specific Activity [micromol/min/mg]
1	Storage Stability
12	Substrates and Products (Substrate)
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 2.6.1.75 - cysteine-conjugate transaminase

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S-(4-bromophenyl)-L-cysteine + 2-oxoglutarate

S-(4-bromophenyl)-3-thiopyruvate + L-glutamate

Rattus norvegicus

highest activity with all three isoenzymes: CAT-I, CAT-IIA, CAT-IIB

640196

additional information

Rattus norvegicus

isoenzyme CAT-I may be involved in in vivo transamination of cysteine conjugates in rat liver, value of reverse reaction is 5 times lower than forward reaction by CAT-I, forward and reverse reaction at similar rates for CAT-IIA and CAT-IIB

640196