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2.6.1.24: diiodotyrosine transaminase

This is an abbreviated version!
For detailed information about diiodotyrosine transaminase, go to the full flat file.

Reaction

3,5-diiodo-L-tyrosine
+
2-oxoglutarate
=
4-hydroxy-3,5-diiodophenylpyruvate
 +
L-glutamate

Synonyms

aminotransferase, diiodotyrosine, diiodotyrosine aminotransferase, EC 2.6.1.25, halogenated tyrosine aminotransferase, halogenated tyrosine transaminase

ECTree

     2 Transferases
         2.6 Transferring nitrogenous groups
             2.6.1 Transaminases
                2.6.1.24 diiodotyrosine transaminase

Substrates Products

Substrates Products on EC 2.6.1.24 - diiodotyrosine transaminase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
3,5-dibromo-L-tyrosine + 2-oxoglutarate
3,5-dibromo-4-hydroxyphenylpyruvate + L-glutamate
show the reaction diagram
-
at 127% the rate of 3,5-diiodo-L-tyrosine
-
-
?
3,5-dichloro-L-tyrosine + 2-oxoglutarate
3,5-dichloro-4-hydroxyphenylpyruvate + L-glutamate
show the reaction diagram
-
at 110% the rate of 3,5-diiodo-L-tyrosine
-
-
?
3,5-diiodo-L-tyrosine + 2-oxoglutarate
3,5-diiodo-4-hydroxyphenylpyruvate + L-glutamate
show the reaction diagram
3,5-diiodo-L-tyrosine + oxaloacetate
3,5-diiodo-4-hydroxyphenylpyruvate + L-aspartate
show the reaction diagram
-
30% substitution of 2-oxoglutarate by oxaloacetate as amino acceptor
-
?
3-(4-fluorophenyl)alanine + 2-oxoglutarate
(4-fluorophenyl)pyruvate + L-glutamate
show the reaction diagram
-
i.e. p-fluoro-DL-phenylalanine, at 3.1% the rate of 3,5-diiodo-L-tyrosine
-
-
?
3-iodo-L-tyrosine + 2-oxoglutarate
3-iodo-4-hydroxyphenylpyruvate + L-glutamate
show the reaction diagram
-
at 76% the rate of 3,5-diiodo-L-tyrosine
-
-
?
L-phenylalanine + 2-oxoglutarate
phenylpyruvate + L-glutamate
show the reaction diagram
-
at 3.9% the rate of 3,5-diiodo-L-tyrosine
-
-
?
L-tryptophan + 2-oxoglutarate
3-indole-2-oxopropanoate + L-glutamate
show the reaction diagram
-
at 3.6% the rate of 3,5-diiodo-L-tyrosine
-
-
?
L-tyrosine + 2-oxoglutarate
(4-hydroxyphenyl)pyruvate + L-glutamate
show the reaction diagram
-
at 3.9% the rate of 3,5-diiodo-L-tyrosine
-
-
?
additional information
?
-