2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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For detailed information about UDP-N-acetylglucosamine 1-carboxyvinyltransferase, go to the full flat file.

Word Map on EC 2.5.1.7

2.5.1.7

peptidoglycan

fosfomycin

pep

cloacae

enterobacter

medicine

epsps

drug development

5-enolpyruvylshikimate

sanguinis

5-enolpyruvylshikimate-3-phosphate

Reaction

UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine

Synonyms

enol-pyruvyltransferase, enolpyruvyl UDP-GlcNAc synthase, enoylpyruvate transferase, enoylpyruvatetransferase, EPT, More, MurA, MurA enzyme, MurA transferase, MurAA, MurZ, phosphoenolpyruvate-UDP-acetylglucosamine-3-enolpyruvyltransferase, phosphoenolpyruvate:UDP-2-acetamido-2-deoxy-D-glucose 2-enoyl-1-carboxyethyltransferase, phosphoenolpyruvate:uridine diphosphate N-acetylglucosamine enolpyruvyltransferase, phosphoenolpyruvate:uridine-5'-diphospho-N-acetyl-2-amino-2-deoxyglucose-3-enolpyruvyltransferase, phosphopyruvate-uridine diphosphoacetylglucosamine pyruvatetransferase, pyruvate-UDP-acetylglucosamine transferase, pyruvate-uridine diphospho-N-acetyl-glucosamine transferase, pyruvate-uridine diphospho-N-acetylglucosamine transferase, pyruvatetransferase, phosphoenolpyruvate-uridine diphosphoacetylglucosamine, pyruvic-uridine diphospho-N-acetylglucosaminyltransferase, UDP-GlcNAc enolpyruvyl transferase, UDP-N-acetylglucosamine 1-carboxyvinyl transferase, UDP-N-acetylglucosamine 1-carboxyvinyl-transferase, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, UDP-N-acetylglucosamine enolpyruvyl transferase, UDP-N-acetylglucosamine enolpyruvyle transferase, UDP-N-acetylglucosamine enolpyruvyltransferase, UDP-N-acetylglucosamine enoylpyruvyltransferase, UDP-N-acetylglucosamine-enolpyruvyl transferase, UDP-NAG enolpyruvyl transferase, UNAG enolpyruvyl transferase

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.7 UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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Results	in table
4	Activating Compound
45128	AA Sequence
12	Application
1	CAS Registry Number
33	Cloned(Commentary)
12	Crystallization (Commentary)
29	General Information
3	General Stability
71	IC50 Value
374	Inhibitors
21	kcat/KM [mM/s]
38	Ki Value [mM]
50	KM Value [mM]
2	Localization
6	Metals/Ions
21	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
387	Organism
9	Pathway
166	PDB ID
13	pH Optimum
4	pH Range
1	pI Value
56	Protein Variants
31	Purification (Commentary)
37	Reaction
1	Reaction Type
104	Reference
10	Specific Activity [micromol/min/mg]
7	Storage Stability
115	Substrates and Products (Substrate)
24	Subunits
126	Synonyms
1	Systematic Name
12	Temperature Optimum [°C]
32	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 2.5.1.7 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase

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34000

gel filtration

37000

nondenaturing PAGE

41000

1 * 41000, SDS-PAGE

42100

42100, SDS-PAGE

44700

44780

44800

MW deduced from amino acid sequence

637593

45000

2 entries

45430

Mycolicibacterium smegmatis

x * 45500, calculated from amino acid sequence

739623

45500

Mycobacterium tuberculosis

739623

45640

Aliivibrio fischeri

B5F9P4

x * 45640, calculated from amino acid sequence

721232

46252

Haemophilus influenzae

1 * 46252, calculated from amino acid sequence, including a C-terminal tag

675932

46300

Haemophilus influenzae

738855

48000

Fusobacterium nucleatum subsp. nucleatum

SDS-PAGE

51000

x * 51000, SDS-PAGE

89000