2.5.1.55: 3-deoxy-8-phosphooctulonate synthase

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For detailed information about 3-deoxy-8-phosphooctulonate synthase, go to the full flat file.

Reaction

Synonyms

2-dehydro-3-deoxy-D-octonate-8-phosphate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating), 2-dehydro-3-deoxyphosphooctonate aldolase, 2-keto-3-deoxy-8-phosphooctonic acid synthetase, 2-keto-3-deoxy-8-phosphooctonic synthetase, 2-keto-3-deoxy-D-manno-octulosonate-8-phosphate synthase, 3-deoxy-D-manno-2-octulosonate-8-phosphate synthase, 3-deoxy-D-manno-2-octulosonic acid-8-phosphate synthase, 3-deoxy-D-manno-octulosonate 8-phosphate synthase, 3-deoxy-D-manno-octulosonate 8-phosphate synthetase, 3-deoxy-D-manno-octulosonate-8-phosphate synthase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, 3-deoxy-D-mannooctulosonate-8-phosphate synthetase, 3-deoxyoctulosonic 8-phosphate synthetase, 3-eoxy-D-manno-octulosonate 8-phosphate synthase, 8-phospho-2-dehydro-3-deoxy-D-octonate D-arabinose-5-phosphate-lyase (pyruvate-phosphorylating), aldolase, phospho-2-keto-3-deoxyoctonate, AtkdsA1, AtkdsA2, EC 4.1.2.16, HpKDO8PS, KDO 8-phosphate synthetase, KDO-8-P synthase, KDO-8-P synthetase, Kdo-8-phosphate synthase, KDO8-P, Kdo8P synthase, KDO8PS, KDOPS, KDPO synthetase, KdsA, KdsA1, KdsA2, metal-independent 3-deoxy-D-manno-octulosonate 8-phosphate synthase, metal-independent KDO8PS, NmeKDO8PS, Phospho-2-dehydro-3-deoxyoctonate aldolase, phospho-2-keto-3-deoxyoctonate aldolase

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.55 3-deoxy-8-phosphooctulonate synthase

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Results	in table
3	Activating Compound
23708	AA Sequence
1	Application
1	CAS Registry Number
26	Cloned(Commentary)
16	Crystallization (Commentary)
9	General Information
5	General Stability
3	IC50 Value
71	Inhibitors
63	kcat/KM [mM/s]
6	Ki Value [mM]
151	KM Value [mM]
1	Localization
70	Metals/Ions
34	Molecular Weight [Da]
19	Natural Substrates/ Products (Substrates)
462	Organism
6	Pathway
192	PDB ID
11	pH Optimum
6	pH Range
36	Protein Variants
22	Purification (Commentary)
10	Reaction
1	Reaction Type
109	Reference
10	Source Tissue
29	Specific Activity [micromol/min/mg]
3	Storage Stability
126	Substrates and Products (Substrate)
27	Subunits
94	Synonyms
1	Systematic Name
8	Temperature Optimum [°C]
4	Temperature Range [°C]
26	Temperature Stability [°C]
110	Turnover Number [1/s]

KI Value

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KI Value on EC 2.5.1.55 - 3-deoxy-8-phosphooctulonate synthase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.0079 - 0.02

1-carboxyheptane-1,7-diyl bis(phosphate)

2 entries

0.6

2,6-Anhydro-3-deoxy-2beta-phosphonylmethyl-8-phosphate-D-glycero-D-talo-octonate

Escherichia coli

-

pH 7.3, 37°C

637408

0.000026

6H-6-Imino-(2,3,4,5-tetrahydropyrimido)[1,2-c]-[1,3]benzothiazine

Escherichia coli

-

pH and temperature not specified in the publication

737981

1

D-ribose 5-phosphate

Escherichia coli

-

pH 7.3, 37°C

637395, 637397

0.0079

1-carboxyheptane-1,7-diyl bis(phosphate)

Neisseria meningitidis

-

pH 7.2, 37°C

721820

0.02

1-carboxyheptane-1,7-diyl bis(phosphate)

Acidithiobacillus ferrooxidans

-

pH 7.2, 37°C

721820