2.5.1.53: uracilylalanine synthase

This is an abbreviated version!
For detailed information about uracilylalanine synthase, go to the full flat file.

Word Map on EC 2.5.1.53

2.5.1.53

thrombospondin

disintegrin

metalloproteinase

cartilage

aggrecan

adamts-4

disintegrin-like

ovulatory

versican

motifs-1

thrombospondin-like

timp-3

aggrecanase-2

Reaction

Synonyms

EC 4.2.99.16, isowillardiine synthase, O3-acetyl-L-serine acetate-lyase, synthase, uracilylalanine, willardiine synthase

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.53 uracilylalanine synthase

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Results	in table
1	CAS Registry Number
6	Cofactor
22	Inhibitors
4	KM Value [mM]
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
9	Organism
1	Pathway
6	pH Optimum
1	pH Range
1	Purification (Commentary)
1	Reaction
1	Reaction Type
9	Reference
6	Source Tissue
1	Specific Activity [micromol/min/mg]
2	Storage Stability
7	Substrates and Products (Substrate)
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 2.5.1.53 - uracilylalanine synthase

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(2,4-Dihydroxypyrimidin-1-yl)-L-alanine

Pisum sativum

i.e. willardiine or 3-(uracil-1-yl)-L-alanine, 30 mM, 84% inhibition of willardiine synthesis and 96% inhibition of isowillardiine synthesis

638057

(2,4-Dihydroxypyrimidin-3-yl)-L-alanine

Pisum sativum

i.e. isowillardiine or 3-(uracil-3-yl)-L-alanine, 30 mM produces 75% inhibition of willardiine synthesis and 93% inhibition of synthesis of isowillardiine

hydroxylamine

KCN

PCMB

0.001 mM, about 90% inhibition

638057

pyridoxal 5'-phosphate

Tris-HCl buffer

Uracil