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2.5.1.39: 4-hydroxybenzoate polyprenyltransferase

This is an abbreviated version!
For detailed information about 4-hydroxybenzoate polyprenyltransferase, go to the full flat file.

Word Map on EC 2.5.1.39

Reaction

a polyprenyl diphosphate
+
4-hydroxybenzoate
=
diphosphate
 +
a 4-hydroxy-3-polyprenylbenzoate

Synonyms

4-hydroxybenzoate octaprenyl transferase, 4-hydroxybenzoate octaprenyltransferase, 4-hydroxybenzoate polyprenyl diphosphate transferase, 4-hydroxybenzoate transferase, 4-hydroxybenzoate:polyprenyl transferase, 4-hydroxybenzoic acid oligoprenyltransferase, 4-para-hydroxybenzoate:polyprenyl transferase, 4-parahydroxybenzoate: polyprenyl transferase, 4HPT, COQ2, Coq2p, dimethylallyltransferase, p-hydroxybenzoate poly-, nonaprenyl-4-hydroxybenzoate transferase, NPHB transferase, OH-benzoate polyprenyltransferase, ORF3, OsPPT1a, p-hydroxybenzoate dimethylallyltransferase, p-hydroxybenzoate polyprenyltransferase, p-hydroxybenzoate:octaprenyltransferase, p-hydroxybenzoate:polyprenyl transferase, p-hydroxybenzoate:polyprenyltransferase, p-hydroxybenzoic acid-polyprenyl transferase, p-hydroxybenzoic-polyprenyl transferase, para-hydroxybenzoate-polyprenyl transferase, PHB-polyprenyltransferase, polyprenyl 4-hydroxybenzoate transferase, PPT, SmPPT, ubiA

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.39 4-hydroxybenzoate polyprenyltransferase

Inhibitors

Inhibitors on EC 2.5.1.39 - 4-hydroxybenzoate polyprenyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,4-dinitrophenol
-
16% inhibition at 1 mM
4-Aminobenzoic acid
-
-
4-Chlorobenzoic acid
-
-
4-nitrobenzoate
acetyl-CoA
-
weak
Ag+
-
complete inhibition at 0.1 mM
bacitracin
-
strong inhibitor
beta-octyl glucoside
-
-
Brij W1
-
inhibition at 0.5% or more, activation at 0.05%
cis-vaccenic acid
-
synonym: cis-11-octadecenoic acid
deoxycholate
-
complete inhibition at 0.5%
Diphenylamine
-
-
Hg2+
-
complete inhibition at 0.1 mM
iodoacetamide
-
-
isopentenyl diphosphate
-
-
N-ethylmaleimide
-
67% inhibition at 1 mM
NaCl
-
increasing concentrations in the presence of 5 mM Mg2+ result in inhibition
Ni2+
-
3.15% of activity remaining at 10 mM
Nonidet P-40
-
inhibition at 0.5% or more, activation at 0.05%
p-chloromercuribenzoate
palmitoyl-CoA
-
-
sodium deoxycholate
Triton X-100
Tween 80
additional information
-
no inhibitor: taurodeoxycholate
-