2.5.1.114: tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase This is an abbreviated version! For detailed information about tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase, go to the full flat file .
Reaction
S-adenosyl-L-methionine +
4-demethylwyosine37 in tRNAPhe =
S-methyl-5'-thioadenosine +
7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe
Synonyms MJ1557, PH0793, TRM12, TYW2, YML005w
ECTree
Engineering
Engineering on EC 2.5.1.114 - tRNAPhe (4-demethylwyosine37-C7) aminocarboxypropyltransferase
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D293A
mutant enzyme retains activity
E265A
mutation eliminates activity
K225A
mutation eliminates activity
T248A
mutant enzyme retains activity
Y242A
mutant enzyme retains activity