2.5.1.103: presqualene diphosphate synthase

This is an abbreviated version!
For detailed information about presqualene diphosphate synthase, go to the full flat file.

Reaction

2 (2E,6E)-farnesyl diphosphate =

Synonyms

squalene synthase, squalene synthase-like, squalene synthase-like 1, squalene synthase-like enzyme, SSL, SSL-1, SSL-2

ECTree

     2 Transferases

         2.5 Transferring alkyl or aryl groups, other than methyl groups

             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

                2.5.1.103 presqualene diphosphate synthase

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Results	in table
1108	AA Sequence
3	Cloned(Commentary)
1	Cofactor
5	General Information
2	Localization
1	Metals/Ions
10	Natural Substrates/ Products (Substrates)
8	Organism
5	Pathway
1	pH Optimum
2	Protein Variants
1	Reaction
6	Reference
12	Substrates and Products (Substrate)
2	Subunits
16	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 2.5.1.103 - presqualene diphosphate synthase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

2 (2E,6E)-farnesyl diphosphate

presqualene diphosphate + diphosphate

5 entries

2 (2E,6E)-farnesyl diphosphate + NADPH + H+

diphosphate + presqualene diphosphate + NADP+

Botryococcus braunii

G0Y286

-

741903

-

-

?

2 geranylgeranyl diphosphate

lycopaoctaene + 2 diphosphate

2 entries

presqualene diphosphate + NADPH + H+

squalene + NADP+ + diphosphate

2 entries

2 (2E,6E)-farnesyl diphosphate

presqualene diphosphate + diphosphate

Botryococcus braunii

G0Y286

-

720917

-

-

?

2 (2E,6E)-farnesyl diphosphate

presqualene diphosphate + diphosphate

Botryococcus braunii

-

reaction of enzyme forms squalene synthase and SSL-1

743340

-

-

?

2 (2E,6E)-farnesyl diphosphate

presqualene diphosphate + diphosphate

Botryococcus braunii Race L

-

reaction of enzyme forms squalene synthase and SSL-1

743340

-

-

?

2 (2E,6E)-farnesyl diphosphate

presqualene diphosphate + diphosphate

Chlamydomonas reinhardtii

-

reaction of isoform SSL-1

758619

-

-

?

2 (2E,6E)-farnesyl diphosphate

presqualene diphosphate + diphosphate

Chlamydomonas reinhardtii CC-125

-

reaction of isoform SSL-1

758619

-

-

?

2 geranylgeranyl diphosphate

lycopaoctaene + 2 diphosphate

Botryococcus braunii

-

reaction of enzyme form SSL-2

743340

-

-

?

2 geranylgeranyl diphosphate

lycopaoctaene + 2 diphosphate

Botryococcus braunii Race L

-

reaction of enzyme form SSL-2

743340

-

-

?

presqualene diphosphate + NADPH + H+

squalene + NADP+ + diphosphate

Botryococcus braunii

-

reaction of enzyme form SSL-2

743340

-

-

?

presqualene diphosphate + NADPH + H+

squalene + NADP+ + diphosphate

Botryococcus braunii Race L

-

reaction of enzyme form SSL-2

743340

-

-

?