2.5.1.103: presqualene diphosphate synthase

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For detailed information about presqualene diphosphate synthase, go to the full flat file.

Word Map on EC 2.5.1.103

2.5.1.103

botryococcus

braunii

botryococcene

microalga

triterpene

Reaction

2 (2E,6E)-farnesyl diphosphate =

Synonyms

squalene synthase, squalene synthase-like, squalene synthase-like 1, squalene synthase-like enzyme, SSL, SSL-1, SSL-2

ECTree

2 Transferases

2.5 Transferring alkyl or aryl groups, other than methyl groups

2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

2.5.1.103 presqualene diphosphate synthase

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Results	in table
1108	AA Sequence
3	Cloned(Commentary)
1	Cofactor
5	General Information
2	Localization
1	Metals/Ions
10	Natural Substrates/ Products (Substrates)
8	Organism
5	Pathway
1	pH Optimum
2	Protein Variants
1	Reaction
6	Reference
12	Substrates and Products (Substrate)
2	Subunits
16	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Systematic Name

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Systematic Name on EC 2.5.1.103 - presqualene diphosphate synthase

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(2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming)

Isolated from the green alga Botryococcus braunii BOT22. Unlike EC 2.5.1.21, squalene synthase, where squalene is formed in one step from farnesyl diphosphate, in this alga the intermediate presqualene diphosphate is generated and released by this enzyme. This compound is then converted into either squalene (by EC 1.3.1.96, Botryococcus squalene synthase) or botryococcene (EC 1.3.1.97, botryococcene synthase).