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2.4.1.94: protein N-acetylglucosaminyltransferase

This is an abbreviated version!
For detailed information about protein N-acetylglucosaminyltransferase, go to the full flat file.

Word Map on EC 2.4.1.94

Reaction

UDP-N-acetyl-D-glucosamine
+
[protein]-L-asparagine
=
UDP
+
[protein]-N4-(N-acetyl-D-glucosaminyl)-L-asparagine

Synonyms

acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-protein, O-GlcNAc transferase, sugar transferase, uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase, uridine diphosphoacetylglucosamine-protein acetylglucosaminyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.94 protein N-acetylglucosaminyltransferase

Inhibitors

Inhibitors on EC 2.4.1.94 - protein N-acetylglucosaminyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Triton X-100
-
at 0.1% and 0.2% concentrations has no effect, at a concentration of 1%, there is a 47% inhibition of enzyme activity
UDP
-
at concentrations of UDP of 0.02, 0.10, and 0.2 mM, the glycosylation of ribonuclease A is inhibited to the extent of 2,15, and 27%, respectively