2.4.1.54: undecaprenyl-phosphate mannosyltransferase
This is an abbreviated version!
For detailed information about undecaprenyl-phosphate mannosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.54
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2.4.1.54
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angiopoietins
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platelet-derived
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angiogenic
-
rottlerin
-
stie-2
-
cdelta
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pkcalpha
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imatinib
-
pkcepsilon
-
vegfr
-
pkcdelta-mediated
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pdgfrs
-
pdgfralpha
-
synthesis
- 2.4.1.54
-
angiopoietins
-
platelet-derived
-
angiogenic
- rottlerin
-
stie-2
-
cdelta
- pkcalpha
- imatinib
- pkcepsilon
- vegfr
-
pkcdelta-mediated
- pdgfrs
- pdgfralpha
- synthesis
Reaction
Synonyms
GDP mannose-undecaprenyl phosphate mannosyltransferase, GDP-D-mannose:lipid phosphate transmannosylase, guanosine diphosphomannose-undecaprenyl phosphate mannosyltransferase, mannosyl-1-phosphoryl-undecaprenol synthetase, mannosylphosphorylundecaprenol synthase, mannosyltransferase, guanosine diphosphomannose-undecaprenyl phosphate, MPU synthetase
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Substrates Products
Substrates Products on EC 2.4.1.54 - undecaprenyl-phosphate mannosyltransferase
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REACTION DIAGRAM
GDPmannose + citronellyl phosphate
GDP + mannosyl-phosphorylcitronellol
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-
beta-isomer as product
?
GDPmannose + dolichyl phosphate
GDP + mannosyl-phosphoryldolichol
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-
beta-isomer as product
?
GDPmannose + phospholipid
GDP + mannosyl-1-phospholipid
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polyprenol type, involved in glycophospholipid biosynthesis
-
-
?
GDPmannose + phytanol phosphate
GDP + D-mannosyl-1-phosphophytanol
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reaction is reversed by GDP, but not by GMP, enzyme is relatively specific for GDPmannose, phytanol phosphate is a poorer glycosyl acceptor than the unidentified endogenous lipid phosphate substrate
-
-
r
GDPmannose + phytol phosphate
GDP + D-mannosyl-1-phosphophytol
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poor substrate
-
-
r
UDPglucose + ficaprenyl phosphate
GDP + glucosyl-1-phosphorylficaprenol
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in the reverse reaction UMP is no substrate
-
-
r
GDP + mannosyl-1-phosphorylficaprenol
-
effective substrate
-
-
?
GDPmannose + ficaprenyl phosphate
GDP + mannosyl-1-phosphorylficaprenol
-
effective substrate
-
?
GDP + mannosyl-phosphorylpolyisoprenol
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endogenous lipid moiety of the glycolipid is a polyprenol and similar to undecaprenyl phosphate, but probably not identical with it, reaction is reversed by GDP, but not by GMP
-
r
GDPmannose + polyisoprenyl phosphate
GDP + mannosyl-phosphorylpolyisoprenol
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mannosylates a wide range of isoprenyl monophosphate substrates
beta-isomer as product
?
GDP + D-mannosyl-1-phosphoundecaprenol
-
-
-
?
GDPmannose + undecaprenyl phosphate
GDP + D-mannosyl-1-phosphoundecaprenol
-
-
-
r
GDPmannose + undecaprenyl phosphate
GDP + D-mannosyl-1-phosphoundecaprenol
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-
Man-P-Undec is an activated mannosyl donor in micrococcal mannan biosynthesis
?
GDPmannose + undecaprenyl phosphate
GDP + D-mannosyl-1-phosphoundecaprenol
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reaction is reversed by GDP
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r
?
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-
no substrates: phosphatidylglycerol, phosphatidylethanolamine, phosphatidylserine, Triton X-100
-
-
?
additional information
?
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-
no substrates: lauryl sulfate, myristyl sulfate, phytol, phytanol, GDPglucose, UDPxylose
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-
?