2.4.1.303: UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase
This is an abbreviated version!
For detailed information about UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase, go to the full flat file.
Word Map on EC 2.4.1.303
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2.4.1.303
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spastic
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paraplegia
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2-hydroxylase
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leukodystrophy
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paraparesis
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2-hydroxylation
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ceramide
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2-hydroxy
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sphingolipids
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pla2g6
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neuroimaging
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galactosylceramide
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sulfatides
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schwann
-
dysarthria
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galactolipids
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medicine
-
analysis
- 2.4.1.303
-
spastic
-
paraplegia
-
2-hydroxylase
-
leukodystrophy
-
paraparesis
-
2-hydroxylation
- ceramide
-
2-hydroxy
-
sphingolipids
-
pla2g6
-
neuroimaging
- galactosylceramide
- sulfatides
-
schwann
-
dysarthria
-
galactolipids
- medicine
- analysis
Reaction
Synonyms
UDP-Gal:GlcNAc-R beta1,3-galactosyltransferase, UDP-Gal:GlcNAc-R galactosyltransferase, UDP-Gal:GlcNAcalpha-pyrophosphate-R beta1,3-galactosyltransferase, WbbD, WbbD beta3Gal-transferase
ECTree
2.4.1.303 UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferaseAdvanced search results
results (
results (Substrates Products
Substrates Products on EC 2.4.1.303 - UDP-Gal:alpha-D-GlcNAc-diphosphoundecaprenol beta-1,3-galactosyltransferase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
UDP-alpha-D-galactose + 1-O-(11-phenoxyundecyl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(11-phenoxyundecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
UDP-alpha-D-galactose + 1-O-(16-phenoxyhexadecyl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(16-phenoxyhexadecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
UDP-alpha-D-galactose + 1-O-(6-phenoxyhex-1-yl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(6-phenoxyhexadecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol. The enzyme does not require a specific length of the lipid chain but can act on GlcNAc-alpha-PO3-PO3-(CH2)R-OPh substrates where R can be 6, 11 or 16 carbons
-
-
?
UDP-alpha-D-galactose + GlcNAc-alpha-PO3-PO3-(CH2)11-O-phenyl
UDP + D-Gal-beta-(1->3)-GlcNAc-alpha-PO3-PO3-(CH2)11-O-phenyl
UDP-alpha-D-galactose + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + beta-D-Gal-beta-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
UDP-alpha-D-galactose + 1-O-(11-phenoxyundecyl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(11-phenoxyundecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
-
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol
-
-
?
UDP-alpha-D-galactose + 1-O-(11-phenoxyundecyl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(11-phenoxyundecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol. The enzyme does not require a specific length of the lipid chain but can act on GlcNAc-alpha-PO3-PO3-(CH2)R-OPh substrates where R can be 6, 11 or 16 carbons
-
-
?
UDP-alpha-D-galactose + 1-O-(11-phenoxyundecyl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(11-phenoxyundecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
-
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol
-
-
?
UDP-alpha-D-galactose + 1-O-(11-phenoxyundecyl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(11-phenoxyundecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol. The enzyme does not require a specific length of the lipid chain but can act on GlcNAc-alpha-PO3-PO3-(CH2)R-OPh substrates where R can be 6, 11 or 16 carbons
-
-
?
UDP-alpha-D-galactose + 1-O-(16-phenoxyhexadecyl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(16-phenoxyhexadecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol. The enzyme does not require a specific length of the lipid chain but can act on GlcNAc-alpha-PO3-PO3-(CH2)R-OPh substrates where R can be 6, 11 or 16 carbons
-
-
?
UDP-alpha-D-galactose + 1-O-(16-phenoxyhexadecyl-diphosphoryl)-alpha-D-glucopyranoside
UDP + 1-O-(16-phenoxyhexadecyl-diphosphoryl)-3-O-beta-D-galactopyranosyl-alpha-D-glucopyranoside
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol. The enzyme does not require a specific length of the lipid chain but can act on GlcNAc-alpha-PO3-PO3-(CH2)R-OPh substrates where R can be 6, 11 or 16 carbons
-
-
?
UDP-alpha-D-galactose + GlcNAc-alpha-PO3-PO3-(CH2)11-O-phenyl
UDP + D-Gal-beta-(1->3)-GlcNAc-alpha-PO3-PO3-(CH2)11-O-phenyl
-
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol
-
-
?
UDP-alpha-D-galactose + GlcNAc-alpha-PO3-PO3-(CH2)11-O-phenyl
UDP + D-Gal-beta-(1->3)-GlcNAc-alpha-PO3-PO3-(CH2)11-O-phenyl
-
synthetic substrate, which is an analog of N-acetyl-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol
-
-
?
UDP-alpha-D-galactose + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + beta-D-Gal-beta-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
the enzyme is involved O7 lipopolysaccharide biosynthesis
-
-
?
UDP-alpha-D-galactose + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + beta-D-Gal-beta-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
the enzyme is specific for UDP-galactose as donor substrate
-
-
?
UDP-alpha-D-galactose + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + beta-D-Gal-beta-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
the enzyme is involved O7 lipopolysaccharide biosynthesis
-
-
?
UDP-alpha-D-galactose + N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
UDP + beta-D-Gal-beta-(1->3)-alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol
the enzyme is specific for UDP-galactose as donor substrate
-
-
?
additional information
?
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WbbD require at least one phosphate in the acceptor substrate which has to be directly linked to GlcNAc, and ise optimally active when GlcNAc is linked to diphosphate. No glycosyl transfer is observed with cytidine-monophosphate N-acetylneuraminic acid, UDP-GalNAc, GDP-Man or UDP-GlcNAc. WbbD does not recognize GlcNAc linked to a glycopeptide
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-
?
additional information
?
-
WbbD require at least one phosphate in the acceptor substrate which has to be directly linked to GlcNAc, and ise optimally active when GlcNAc is linked to diphosphate. No glycosyl transfer is observed with cytidine-monophosphate N-acetylneuraminic acid, UDP-GalNAc, GDP-Man or UDP-GlcNAc. WbbD does not recognize GlcNAc linked to a glycopeptide
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-
?
