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2.4.1.301: 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase

This is an abbreviated version!
For detailed information about 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase, go to the full flat file.

Reaction

UDP-alpha-D-kanosamine
+
2'-deamino-2'-hydroxyneamine
=
UDP
+
kanamycin A

Synonyms

KanE, KanM2

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.301 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase

Systematic Name

Systematic Name on EC 2.4.1.301 - 2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase

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SYSTEMATIC NAME
IUBMB Comments
UDP-alpha-D-kanosamine:2'-deamino-2'-hydroxyneamine 1-alpha-D-kanosaminyltransferase
Involved in the biosynthetic pathway of kanamycins. The enzyme characterized from the bacterium Streptomyces kanamyceticus can also accept UDP-alpha-D-glucose with lower efficiency [2].