2.4.1.250: D-inositol-3-phosphate glycosyltransferase
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For detailed information about D-inositol-3-phosphate glycosyltransferase, go to the full flat file.
Reaction
Synonyms
CgMshA, MshA, MSMEG0924, mycothiol glycosyltransferases
ECTree
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Systematic Name
Systematic Name on EC 2.4.1.250 - D-inositol-3-phosphate glycosyltransferase
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UDP-N-acetyl-D-glucosamine:1D-myo-inositol 3-phosphate alpha-D-glycosyltransferase
The enzyme, which belongs to the GT-B fold superfamily, catalyses the first dedicated reaction in the biosynthesis of mycothiol [1]. The substrate was initially believed to be inositol, but eventually shown to be D-myo-inositol 3-phosphate [2]. A substantial conformational change occurs upon UDP binding, which generates the binding site for D-myo-inositol 3-phosphate [3].