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2.4.1.194: 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase

This is an abbreviated version!
For detailed information about 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase, go to the full flat file.

Reaction

UDP-glucose
+
4-hydroxybenzoate
=
UDP
 +
4-(beta-D-glucosyloxy)benzoate

Synonyms

HBA glucosyltransferase, p-hydroxybenzoate glucosyltransferase, PHB glucosyltransferase, PHB-O-glucosyltransferase, UDP-glucose:4-(beta-D-glucopyranosyloxy)benzoic acid glucosyltransferase, uridine diphosphoglucose-4-hydroxybenzoate glucosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.194 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase

Inhibitors

Inhibitors on EC 2.4.1.194 - 4-hydroxybenzoate 4-O-beta-D-glucosyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-hydroxybenzoic acid
-
-
3-Hydroxybenzoic acid
-
competitive inhibition
4-(beta-D-glucosyloxy)benzoate
-
non competitive inhibition with respect to both 4-hidroxybenzoic acid and UDP
4-coumaric acid
-
-
4-hydroxybenzoic acid
-
-
Ca2+
-
weak effect
Co2+
-
strong inhibition at 1 mM and 10 mM
Cu2+
-
strong inhibition at 1 mM and 10 mM
EDTA
-
negative influence on activity at 10 mM, but reversible
Fe2+
-
strong inhibition at 1 mM and 10 mM
gallic acid
-
competitive inhibition
Mg2+
-
weak effect
Mn2+
-
weak effect
Ni2+
-
strong inhibition at 1 mM and 10 mM
UDP
-
non competitive inhibition with respect to 4-hydroxybenzoic acid, competitive inhibitor with respect to UDPglucose
vanillic acid
-
competitive inhibition
Zn2+
-
strong inhibition at 1 mM and 10 mM