2.4.1.142: chitobiosyldiphosphodolichol beta-mannosyltransferase

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For detailed information about chitobiosyldiphosphodolichol beta-mannosyltransferase, go to the full flat file.

Reaction

Synonyms

ALG1, ALG1 beta1,4 mannosyltransferase, Alg1 mannosyltransferase, Alg1 protein, Alg1p, beta-1,4 mannosyltransferase, beta1,4-MT, chitobiosyldiphosphodolichol beta-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase, guanosine diphosphate-mannose:GlcNAc2-PP-dolichol mannosyltransferase-1, guanosine diphosphomannose-dolichol diphosphochitobiose mannosyltransferase, mannosyltransferase I, MT-1, MT-I

ECTree

     2 Transferases

         2.4 Glycosyltransferases

             2.4.1 Hexosyltransferases

                2.4.1.142 chitobiosyldiphosphodolichol beta-mannosyltransferase

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Results	in table
7	Activating Compound
1336	AA Sequence
1	Application
1	CAS Registry Number
8	Cloned(Commentary)
9	Disease/ Diagnostics
1	Expression
7	General Information
9	Inhibitors
2	KM Value [mM]
9	Localization
4	Metals/Ions
11	Natural Substrates/ Products (Substrates)
17	Organism
6	Pathway
4	pH Optimum
26	Protein Variants
3	Purification (Commentary)
1	Reaction
1	Reaction Type
15	Reference
15	Source Tissue
2	Specific Activity [micromol/min/mg]
2	Storage Stability
19	Substrates and Products (Substrate)
1	Subunits
23	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]

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Application on EC 2.4.1.142 - chitobiosyldiphosphodolichol beta-mannosyltransferase

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

pharmacology

Rattus norvegicus

D4A5S6

the WD repeat domain 3 (WDR3) and chitobiosyldiphosphodolichol beta-mannosyltransferase (ALG1) genes are target candidates for schizophrenia-related molecules, whose mRNAs are upregulated in the adult (postnatal week seven), but not in the infant (postnatal week one) rats by an indirect dopamine agonist, and phencyclidine, an antagonist of the NMDA receptor

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