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2.3.2.7: aspartyltransferase

This is an abbreviated version!
For detailed information about aspartyltransferase, go to the full flat file.

Reaction

L-asparagine
+
hydroxylamine
=
NH3
 +
beta-L-aspartylhydroxamate

Synonyms

aspartotransferase, BAT, BAT-GGT, beta-aspartyl transferase, beta-aspartyl-gamma-glutamyltransferase, beta-aspartyltransferase

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.2 Aminoacyltransferases
                2.3.2.7 aspartyltransferase

Inhibitors

Inhibitors on EC 2.3.2.7 - aspartyltransferase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
dithiothreitol
-
slight inhibition at 5 mM
EDTA
-
slight inhibition at 5 mM
L-aspartate
-
20 mM, 30% inhibition
L-cysteine
-
5 mM, 50% inhibition
PCMB
-
reversible by GSH, 2-mercaptoethanol or 2,3-dimercaptopropanol, not L-cysteine
streptomycin
-
5 mM, 50% inhibition
additional information
-
no inhibition by NaN3, isonicotinic acid hydrazide, L-homoserine, L-glutamic acid, terminal amino acids of aspartic acid pathway, i.e. lysine, threonine, methionine and isoleucine, up to 20 mM
-